US 421, I 65 $south
706.4 mi11 hours 59 mins
| Head north on South Washington Street | 100 feet | |
| Turn left onto Austin Street | 400 feet | |
| Turn left onto South Adams Street (US 421) | 20.6 mi | |
| Turn right onto North Michigan Road | 1.5 mi | |
| Turn right onto Clifty Drive (SR 62) | 5.6 mi | |
| Turn right onto SR 56 | 12.0 mi | |
| Turn left onto SR 3 | 8.3 mi | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto I 65 S | 199.4 mi | |
| Keep left towards I 24 East: Nashville | 2.4 mi | |
| Keep left towards I 24 East: Chattanooga | 2.8 mi | |
| Keep right towards I 40 West: Memphis | 0.4 mi | |
| Merge left onto I 40 | 0.6 mi | |
| Keep left towards I 65 South: Huntsville | 0.4 mi | |
| Merge right onto I 65 S | 28.8 mi | |
| Keep left onto I-65 (I 65 S) | 66.1 mi | |
| Continue onto I 65 (I 65 S) | 0.2 mi | |
| Continue onto I-65 (I 65 S) | 239.7 mi | |
| Take the ramp towards 106: Georgiana | 0.3 mi | |
| Turn left onto SR 106 | 1.5 mi | |
| Continue onto SR 55 | 7.9 mi | |
| Continue onto Crum Foshee Highway (AL 55) | 18.0 mi | |
| Turn left onto US 84 | 0.8 mi | |
| Continue onto US 84 | 0.3 mi | |
| Continue onto River Falls Street (US 84) | 2.6 mi | |
| Turn right to stay on River Falls Street (US 29) | 500 feet | |
| Continue onto Western Bypass (US 29) | 11.2 mi | |
| Make a slight left onto SR 137 | 14.0 mi | |
| Continue onto State Highway 189 (FL 189) | 14.5 mi | |
| Continue onto FL 4 | 4.5 mi | |
| Turn left onto US 90 | 4.3 mi | |
| Turn right onto South Ferdon Boulevard (FL 85) | 14.2 mi | |
| Keep left onto FL 85 | 2.3 mi | |
| Take the ramp towards FL 293 Toll | 0.6 mi | |
| Continue onto Mid-Bay Bridge Connector (FL 293 Toll) | 15.5 mi | |
| Turn right onto Emerald Coast Parkway (US 98) | 4.3 mi | |
| Turn right onto Benning Drive | 400 feet | |
| You have arrived at your destination |
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47042, Versailles, Indiana - Destin, Florida