I 20, TX 6
422.5 mi6 hours 57 mins
| Head east on South 1st Street (I 20-R Business) | 0.8 mi | |
| Keep left onto South Treadaway Boulevard (I 20-R Business) | 600 feet | |
| Turn right to stay on I 20-R Business | 5.3 mi | |
| Take the ramp onto I 20-R Business | 139.1 mi | |
| Keep left onto Ronald Reagan Memorial Highway (I 20) | 1.7 mi | |
| Keep left at the fork | 700 feet | |
| Continue onto Ronald Reagan Memorial Highway (I 20) | 2.7 mi | |
| Keep right at the fork | 1,000 feet | |
| Keep left at the fork | 100 feet | |
| Keep right at the fork | 0.4 mi | |
| Keep right towards I 35W South: Waco | 0.5 mi | |
| Merge left onto South Freeway (I 35W S) | 45.4 mi | |
| Continue onto I 35 S | 6.8 mi | |
| Keep left onto I 35 S | 26.3 mi | |
| Take the ramp towards US 77 (North Loop Drive) | 800 feet | |
| Go straight onto Interstate Highway 35 Service Road | 0.4 mi | |
| Turn left onto North Loop Drive | 0.2 mi | |
| Take the ramp on the left | 400 feet | |
| Merge left onto US 77-L Business S | 0.7 mi | |
| Continue onto Marlin Highway (Loop 484 E) | 2.7 mi | |
| Continue onto TX 6 | 49.5 mi | |
| Merge left onto Main Street (TX 6) | 37.1 mi | |
| Continue onto East Bypass (TX 6 S) | 39.1 mi | |
| Continue onto US 290-H Business | 400 feet | |
| Take the ramp on the left | 0.4 mi | |
| Merge left onto Northwest Freeway (US 290) | 32.2 mi | |
| Keep right onto Northwest Freeway (US 290) | 10.4 mi | |
| Take the ramp towards Mangum Road | 500 feet | |
| Merge right onto Northwest Freeway Frontage Road | 1.6 mi | |
| Keep right onto Northwest Freeway Frontage Road | 700 feet | |
| Turn left onto Hempstead Highway | 1.5 mi | |
| Continue onto Washington Avenue | 0.4 mi | |
| Continue onto Westcott Street | 500 feet | |
| Take the ramp on the left towards I 10 East | 0.2 mi | |
| Merge left onto Katy Freeway (I 10) | 3.6 mi | |
| Take the ramp on the left towards I 45 South: Galveston | 800 feet | |
| Merge left onto I 45 S | 10.1 mi | |
| Take the ramp towards TX 3: Monroe Road | 900 feet | |
| Go straight onto Gulf Freeway Frontage Road | 0.3 mi | |
| Turn left onto Monroe Road (TX 3) | 1,000 feet | |
| Continue onto Winkler Drive (TX 3) | 1.1 mi | |
| Turn right onto Galveston Road (TX 3) | 0.4 mi | |
| Turn right onto Georgia Street | 500 feet | |
| Turn left onto Dallas Street | 200 feet | |
| You have arrived at your destination, on the left |
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Abilene, Texas - South Houston, Texas