I 80, I 80; US 6
148.7 mi2 hours 30 mins
| Head north on Grand Avenue (I 35 Business) | 500 feet | |
| Turn right onto 6th Street | 0.5 mi | |
| Turn right onto Duff Avenue | 1.6 mi | |
| Take the ramp on the right towards US 30 east: Nevada | 1.1 mi | |
| Continue onto I 35 Bus S | 0.8 mi | |
| Take the ramp towards I 35 Business South: Des Moines | 0.6 mi | |
| Merge left onto I 35 S | 24.8 mi | |
| Continue onto I 235 W | 13.7 mi | |
| Continue onto I 80 | 81.9 mi | |
| Take the ramp towards US 59: Avoca | 0.3 mi | |
| Turn right onto US 59 | 19.3 mi | |
| Turn left onto State Highway 37 (IA 37) | 3.5 mi | |
| Continue onto Railway Street (IA 37) | 0.5 mi | |
| Turn right onto 4th Avenue | 200 feet | |
| You have arrived at your destination |
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Ames, Iowa - Earling, Iowa