I 99 $north; US 220 $north, US 219
413.7 mi7 hours 20 mins
| Head southwest on Columbia Pike (VA 244) | 0 feet | |
| Turn right onto Little River Turnpike (VA 236) | 1.1 mi | |
| Take the ramp on the right towards I 495 North: Tysons Corner | 0.4 mi | |
| Merge left onto Capital Beltway (I 495 N) | 13.2 mi | |
| Keep left towards I 270: Rockville | 1.4 mi | |
| Continue onto I 270 Spur N | 0.9 mi | |
| Merge left onto I 270 N | 0.8 mi | |
| Keep right towards I 270 North | 28.3 mi | |
| Take the ramp towards I 70: Hagerstown | 0.4 mi | |
| Keep left towards I 70 West: Hagerstown | 0.4 mi | |
| Merge right onto I 70 | 76.1 mi | |
| Merge left onto Lincoln Highway (US 30) | 1,000 feet | |
| Turn right onto I 70 W | 1.6 mi | |
| Keep right towards I 70 West: Pittsburgh | 0.4 mi | |
| Merge left onto Pennsylvania Turnpike (I 70 W) | 15.5 mi | |
| Take the ramp towards Altoona | 0.3 mi | |
| Keep left towards Altoona | 100 feet | |
| Turn left onto North Richard Street (US 220 Business) | 0.3 mi | |
| Take the ramp on the left towards I 99: Cumberland | 0.2 mi | |
| Keep right towards I 99 North: Altoona | 0.3 mi | |
| Merge left onto I 99 N | 50.9 mi | |
| Take the ramp towards PA 350: Bald Eagle | 0.6 mi | |
| Turn left onto US 220 Business | 2.2 mi | |
| Continue onto S Centre St (PA 350) | 11.1 mi | |
| Continue onto Tyrone Pike (PA 350) | 0.5 mi | |
| Continue onto South Centre Street (PA 350) | 1.4 mi | |
| Continue onto North Front Street (US 322) | 0.3 mi | |
| Continue onto Philipsburg Bigler Highway (US 322) | 7.1 mi | |
| Continue onto Woodland Bigler Highway (US 322) | 2.8 mi | |
| Turn right onto Shawville Highway (PA 970) | 1.6 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 80 | 25.6 mi | |
| Take the ramp towards US 219: DuBois | 0.5 mi | |
| Keep right towards US 219: DuBois | 400 feet | |
| Merge left onto Rich Highway (US 219) | 7.2 mi | |
| Continue onto Clark Street (US 219) | 600 feet | |
| Turn right onto Main Street (US 219) | 16.9 mi | |
| Continue onto East Main Street (US 219) | 0.5 mi | |
| Turn right onto North Broad Street (US 219) | 0.3 mi | |
| Continue onto N Broad Street (US 219) | 1.5 mi | |
| Continue onto Ridgway-Johnsonburg Road (US 219) | 5.5 mi | |
| Continue onto East Center Street (US 219) | 0.2 mi | |
| Keep left onto East Center Street (US 219) | 300 feet | |
| Continue onto Johnsonburg Bypass (US 219) | 1.2 mi | |
| Continue onto Market Street (US 219) | 1.2 mi | |
| Continue onto Wilcox Road (US 219) | 4.1 mi | |
| Take the ramp onto US 219 | 39.6 mi | |
| Take the ramp on the left onto US 219 N | 0.4 mi | |
| Merge left onto Southern Tier Expressway (I 86 W) | 6.3 mi | |
| Take exit 21 towards US 219 North: Salamanca | 0.4 mi | |
| Turn right onto Parkway Drive (US 219) | 500 feet | |
| Turn right onto Wildwood Avenue (US 219) | 0.7 mi | |
| Turn left onto Central Avenue (US 219) | 0.9 mi | |
| Continue onto Salamanca Great Valley (US 219) | 4.3 mi | |
| Turn left onto US 219 | 4.8 mi | |
| Turn right onto Washington Street (US 219) | 1.0 mi | |
| Turn left onto US 219 | 13.7 mi | |
| Turn right onto Peters Road (US 219) | 0.3 mi | |
| Continue onto Peters Rd (US 219) | 500 feet | |
| Take the ramp on the left onto US 219 N | 28.2 mi | |
| Merge left onto New York State Thruway (I 90 E) | 8.2 mi | |
| Take exit 50 towards I 290: Niagara Falls | 0.7 mi | |
| Continue onto Youngmann Expressway (I 290 W) | 3.5 mi | |
| Take the ramp towards I 990: University at Buffalo | 0.4 mi | |
| Continue onto Staff Sergeant William R. Wilson III Memorial Highway (I 990 N) | 0.4 mi | |
| Continue onto Lockport Expressway (I 990 N) | 5.4 mi | |
| Turn left onto Millersport Highway (NY 263) | 3.1 mi | |
| Turn left onto Transit Road (NY 78) | 4.8 mi | |
| Continue onto South Transit Street (NY 78) | 1.2 mi | |
| Turn right onto Main Street | 500 feet | |
| You have arrived at your destination |
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Annandale, Virginia - Lockport, New York