I 64 $west, I 65 $south
331.8 mi5 hours 37 mins
| Head northwest on Winchester Avenue (US 60) | 100 feet | |
| Turn left onto Martin Luther King Junior Boulevard (US 60) | 0.5 mi | |
| Go straight onto 13th Street (US 60) | 3.1 mi | |
| Continue onto Purple Heart Highway (US 60) | 4.6 mi | |
| Continue onto KY 180 | 1.5 mi | |
| Take the ramp | 0.5 mi | |
| Merge left onto I 64 W | 103.1 mi | |
| Keep right towards I 64 West: Louisville | 2.4 mi | |
| Take the ramp towards US 27: Paris | 0.4 mi | |
| Turn right onto North Broadway (US 27) | 1.2 mi | |
| Turn right onto New Circle Road (KY 4) | 5.8 mi | |
| Take the ramp | 0.4 mi | |
| Merge left onto Versailles Road (US 60) | 4.5 mi | |
| Continue onto Lexington Road (US 60) | 1.3 mi | |
| Keep right towards Elizabethtown | 72.0 mi | |
| Merge left onto I 65 S | 125.8 mi | |
| Keep left towards I 24 East: Nashville | 2.4 mi | |
| Keep left towards I 24 East: Chattanooga | 1.4 mi | |
| Take exit 48 towards State Capitol | 900 feet | |
| Continue onto Interstate Drive | 400 feet | |
| Turn right onto James Robertson Parkway (US 31) | 0.6 mi | |
| You have arrived at your destination |
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Ashland, Kentucky - Nashville, Tennessee