How to get from Athens, Alabama to Tupelo, Mississippi

Discover, print or download the driving directions for the best route to go from Athens, Alabama to Tupelo, Mississippi.

Enlarge the route map Athens, Alabama - Tupelo, Mississippi

Driving directions from Athens, Alabama to Tupelo, Mississippi

US 72, US 45

143.5 mi2 hours 33 mins

Head west on Hobbs Street West 200 feet
Turn left onto Jefferson Street North 800 feet
Turn right onto Washington Street West 1.7 mi
Turn left onto Lucas Ferry Road 0.3 mi
Turn right onto US Highway 72 (US 72) 40.0 mi
Continue onto East Tennessee Street (US 43) 0.2 mi
Continue slightly left onto East Dr Hicks Boulevard (US 43) 0.6 mi
Turn left onto South Court Street (US 43) 1.3 mi
Continue onto N Jackson Hwy (US 43) 0.3 mi
Continue onto Woodward Avenue (US 43) 0.2 mi
Turn left onto Woodward Avenue (US 43) 4.2 mi
Take the ramp onto US 72 39.4 mi
Take the ramp 600 feet
Keep right at the fork 400 feet
Go straight onto MS 365 8.5 mi
Turn right onto MS 364 11.6 mi
Turn right onto MS 30 6.6 mi
Keep left onto MS 30 6.4 mi
Continue onto US 45 20.3 mi
Take the ramp towards Downtown Tupelo 0.3 mi
Continue onto North Front Street 0.9 mi
Turn right onto West Main Street 0.3 mi
You have arrived at your destination

Print directions
Athens, Alabama - Tupelo, Mississippi

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.