US 160 $east, Dwight D. Eisenhower Highway
725.4 mi11 hours 33 mins
| Head northwest on South Buck Highway | 200 feet | |
| Turn right onto US 160 Business | 0.9 mi | |
| Turn right onto US 160 E | 70.1 mi | |
| Make a slight left onto US 160 E | 59.3 mi | |
| Turn left onto Denver Avenue (US 160 E) | 0.2 mi | |
| Continue onto Broadway Avenue (US 160 E) | 0.3 mi | |
| Continue onto Santa Fe Avenue (US 160 E) | 20.6 mi | |
| Continue onto US Highway 160 (US 160 E) | 3.2 mi | |
| Continue onto 4th Street (US 160 E) | 47.6 mi | |
| Turn left onto Main Street (I 25 Business) | 800 feet | |
| Turn right onto East 5th Street (US 160 E) | 0.5 mi | |
| Continue onto First Cavalry Division Memorial Highway (US 160 E) | 71.3 mi | |
| Continue onto 4th Street (CO 10) | 0.5 mi | |
| Continue slightly left onto Dalton Avenue (CO 10) | 0.3 mi | |
| Turn right onto US 50 E | 55.0 mi | |
| Turn left onto CR KK | 16.8 mi | |
| Turn left onto South Labelle Avenue (US 385) | 24.2 mi | |
| Turn right onto Main Street (US 385) | 0.8 mi | |
| Turn left onto Colorado Avenue (US 385) | 0.3 mi | |
| Continue slightly left onto Borders Street (US 385) | 25.8 mi | |
| Turn right onto United States Highway 40 (US 40) | 86.9 mi | |
| Take the ramp onto US 40 E | 900 feet | |
| Merge left onto Dwight D. Eisenhower Highway (I 70) | 226.1 mi | |
| Take the ramp towards KS 18 East: Manhattan | 0.3 mi | |
| Turn left onto KS 18 | 13.8 mi | |
| Turn left onto South 4th Street | 0.3 mi | |
| You have arrived at your destination |
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Bayfield, Colorado - Manhattan, Kansas