National Freeway, I 81 $north
341.6 mi5 hours 48 mins
| Head northeast on Junior-Philippi-Grafton Road (US 250) | 8.4 mi | |
| Continue onto Barbour County Highway (US 250) | 2.4 mi | |
| Continue onto South Main Street (US 250) | 1.2 mi | |
| Continue onto Pike Street (US 250) | 500 feet | |
| Continue onto Beverly-Fairmont Pike (US 250) | 500 feet | |
| Turn right onto Beverley - Fairmont Pike (US 119) | 14.8 mi | |
| Turn left onto US 119 | 1.6 mi | |
| Go straight onto Victory Avenue (US 119) | 10.1 mi | |
| Continue onto Grafton Road (US 119) | 10.2 mi | |
| Turn left | 0.3 mi | |
| Merge left onto I 68 E | 110.6 mi | |
| Keep right towards I 70 East: Hagerstown | 600 feet | |
| Keep left towards I 70 East: Hagerstown | 0.4 mi | |
| Merge left onto Dwight David Eisenhower Highway (I 70) | 600 feet | |
| Continue onto Dwight D Eisenhower Highway (I 70) | 4.7 mi | |
| Continue onto I 70, US 40 (Dwight D Eisenhower Highway) (I 70) | 3.2 mi | |
| Continue onto Dwight D Eisenhower Highway (I 70) | 16.2 mi | |
| Take the ramp towards I 81: Roanoke | 600 feet | |
| Keep left towards I 81 North: Harrisburg | 0.3 mi | |
| Keep right towards I 81 North: Hagerstown | 0.3 mi | |
| Keep left towards I 81 North: Harrisburg | 0.4 mi | |
| Merge left onto Maryland Veterans Memorial Highway (I 81 N) | 73.0 mi | |
| Continue onto George N Wade Bridge (I 81 N) | 1.0 mi | |
| Continue onto American Legion Memorial Highway (I 81 N) | 22.5 mi | |
| Keep right towards I 78 East: Allentown | 50.9 mi | |
| Keep right towards US 22 East: LVI Airport | 6.5 mi | |
| Take the ramp towards PA 145 | 800 feet | |
| Keep right towards PA 145 South: Allentown | 300 feet | |
| Merge left onto MacArthur Road (PA 145 S) | 0.6 mi | |
| Continue onto North 7th Street (PA 145) | 1.1 mi | |
| Turn left onto West Hamilton Street | 700 feet | |
| You have arrived at your destination | 0 feet |
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Belington, West Virginia - Allentown, Pennsylvania