How to get from Cairo, Missouri to Clarksville, Missouri

Discover, print or download the driving directions for the best route to go from Cairo, Missouri to Clarksville, Missouri.

Enlarge the route map Cairo, Missouri - Clarksville, Missouri

Driving directions from Cairo, Missouri to Clarksville, Missouri

MO 22, US 54

114.7 mi2 hours 11 mins

Head east on East Martin Street (MO Z) 0.2 mi
Turn right onto US 63 S 20.2 mi
Take the ramp towards MO 22: Centralia 0.2 mi
Turn right onto MO 22 24.6 mi
Turn right onto North Western (MO 15) 300 feet
Continue onto South Muldrow Street (MO 15) 0.6 mi
Turn left onto West Boulevard Street (MO 15) 0.6 mi
Continue onto Green Boulevard (US 54 Business) 0.6 mi
Turn right onto East Liberty Street (US 54 Business) 12.2 mi
Turn left onto US 54 8.1 mi
Turn right to stay on US 54 36.6 mi
Turn right onto North 3rd Street (US 54 Business) 10.7 mi
You have arrived at your destination

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Cairo, Missouri - Clarksville, Missouri

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