I 94 $east, Highway 402
730.6 mi12 hours 15 mins
| Head southeast on West Greene Street (US 52) | 0.2 mi | |
| Continue onto Main Street (US 52) | 5.1 mi | |
| Turn left onto US 18 | 1.1 mi | |
| Turn right onto South Lawler Street (US 18) | 700 feet | |
| Turn left onto East Military Road (US 18) | 15.1 mi | |
| Turn right onto US 52 | 33.6 mi | |
| Turn left onto 1st Street East (US 52) | 0.2 mi | |
| Turn left onto US 52 | 23.5 mi | |
| Turn left onto East 32nd Street | 500 feet | |
| Turn right onto Jackson Street | 1.7 mi | |
| Turn left onto East 14th Street | 600 feet | |
| Turn right onto Elm Street | 0.3 mi | |
| Take the ramp on the right onto US 52 S | 0.6 mi | |
| Turn right | 700 feet | |
| Merge right onto South Locust Street | 600 feet | |
| Turn left onto Dodge Street (US 20) | 900 feet | |
| Continue onto Julien Dubuque Bridge (US 20) | 14.8 mi | |
| Continue onto Decatur Street (US 20) | 14.3 mi | |
| Continue onto West Diagonal Street (US 20) | 600 feet | |
| Continue onto North Main Street (US 20) | 71.4 mi | |
| Continue onto I 39 N | 0.6 mi | |
| Keep right towards I 90 East: Chicago | 0.4 mi | |
| Merge left onto Jane Addams Memorial Tollway (I 90) | 19.8 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90) | 40.5 mi | |
| Keep left onto Jane Addams Memorial Tollway (I 90 E) | 1.0 mi | |
| Merge right onto Kennedy Expressway (I 90) | 5.6 mi | |
| Keep right onto Kennedy Expressway (I 90) | 8.3 mi | |
| Continue onto Dan Ryan Expressway (I 90) | 2.4 mi | |
| Keep left towards I 90 Express | 3.8 mi | |
| Take the ramp towards I 90 East: Chicago Skyway | 0.4 mi | |
| Merge right onto Dan Ryan Expressway (I 90) | 0.5 mi | |
| Keep left towards I 90 East: Chicago Skyway | 10.6 mi | |
| Keep left onto Indiana Toll Road (I 90) | 17.4 mi | |
| Take the ramp towards I 94: Detroit | 0.7 mi | |
| Keep left at the fork | 0.6 mi | |
| Merge left onto I 94 E | 200.4 mi | |
| Keep right towards I 94: Detroit | 105.1 mi | |
| Continue onto CBSA - Sarnia (Point Edward) Point Of Entry Traveler Lanes (402 E) | 63.9 mi | |
| Merge left onto Highway 401 (401 E) | 31.1 mi | |
| Keep left onto Highway 401 (401 E) | 24.8 mi | |
| Take the ramp towards 28: Kitchener | 0.3 mi | |
| Turn left onto Fountain Street South (28) | 700 feet | |
| Continue onto Homer Watson Boulevard (28) | 4.4 mi | |
| Enter the roundabout and take the 2nd exit onto Homer Watson Boulevard (28) | 100 feet | |
| Exit the roundabout onto Homer Watson Boulevard (28) | 0.8 mi | |
| Enter the roundabout and take the 1st exit onto Homer Watson Boulevard (28) | 200 feet | |
| Exit the roundabout onto Homer Watson Boulevard (28) | 0.4 mi | |
| Turn right onto Hoffman Street | 600 feet | |
| Turn left onto Highland Road East | 1.4 mi | |
| Turn right onto Belmont Avenue West | 1.2 mi | |
| Turn right onto Union Boulevard | 1,000 feet | |
| Turn left onto Park Street | 0.4 mi | |
| Make a slight right | 100 feet | |
| Turn right onto William Street West | 0.3 mi | |
| Turn left | 200 feet | |
| You have arrived at your destination, straight ahead |
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Castalia, Iowa - Waterloo, Ontario