I 64 $west, I 75 $south
493.4 mi8 hours
| Head north on Walnut Street (US 23) | 300 feet | |
| Make a U-turn and continue on Walnut Street (US 23) | 0.4 mi | |
| Continue onto Louisa Street (US 23) | 1.1 mi | |
| Continue onto Louisa Road (US 23) | 1.1 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 64 W | 93.8 mi | |
| Take the ramp towards KY 627: Paris | 0.3 mi | |
| Turn left onto Paris Road (KY 627) | 0.5 mi | |
| Continue onto North Maple Street (KY 627) | 1.3 mi | |
| Turn right onto Boone Avenue (KY 627) | 1.3 mi | |
| Continue onto Boonesboro Road (KY 627) | 12.4 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 75 S | 148.1 mi | |
| Take the ramp towards I 75 South: Nashville | 3.5 mi | |
| Keep right towards I 75 South: Nashville | 17.1 mi | |
| Keep left towards I 75 South: Chattanooga | 10.2 mi | |
| Keep right onto I 75 S | 800 feet | |
| Keep left onto I 75 S | 49.5 mi | |
| Take the ramp towards SR 60: Cleveland | 1,000 feet | |
| Turn right onto Georgetown Road Northwest (TN 60) | 1,000 feet | |
| Continue onto 25th Street Northwest (TN 60) | 4.1 mi | |
| Continue onto Appalachian Highway (US 74) | 1.7 mi | |
| Turn left onto McGrady Drive Southeast (TN 60) | 0.2 mi | |
| Turn left onto Dalton Pike (TN 60) | 10.7 mi | |
| Continue onto Cleveland Road (GA 71) | 9.1 mi | |
| Continue onto Cleveland Highway (GA 71) | 4.5 mi | |
| Turn right onto North Bypass (US 41) | 2.1 mi | |
| Continue onto Chattanooga Road (US 41) | 0.6 mi | |
| Take the ramp on the left | 0.3 mi | |
| Merge left onto I 75 S | 90.3 mi | |
| Continue onto James Wendell George Parkway (I 75 S) | 2.3 mi | |
| Keep left onto I 75 S | 21.4 mi | |
| Take the ramp towards Jonesboro Road | 0.2 mi | |
| Turn left onto Jonesboro Road | 3.6 mi | |
| Continue onto Jonesboro Street | 0.4 mi | |
| You have arrived at your destination |
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Catlettsburg, Kentucky - McDonough, Georgia