How to get from Charleston, West Virginia to O'Fallon, Missouri

Discover, print or download the driving directions for the best route to go from Charleston, West Virginia to O'Fallon, Missouri.

Enlarge the route map Charleston, West Virginia - O'Fallon, Missouri

Driving directions from Charleston, West Virginia to O'Fallon, Missouri

I 64 $west, I 70 $west

536.0 mi8 hours 19 mins

Head northwest on Kanawha Boulevard East 0.5 mi
Make a slight right towards I 64: Huntington 600 feet
Take the ramp towards I 64 West: Huntington 26.1 mi
Continue onto I 64 W 141.2 mi
Keep right towards I 64 West: Louisville 6.9 mi
Keep left towards I 64 West: Frankfort 250.3 mi
Keep right towards I 57 North 4.6 mi
Take the ramp on the left towards I 64 West: Saint Louis 70.7 mi
Take the ramp towards I 70 West: Kansas City 0.7 mi
Merge right onto I 70 W 33.3 mi
Take exit 218 400 feet
Go straight onto East Terra Lane 0.9 mi
Turn right onto South Main Street 0.5 mi
You have arrived at your destination

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Charleston, West Virginia - O'Fallon, Missouri

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