How to get from Charlotte, North Carolina to Lancaster, Pennsylvania

Discover, print or download the driving directions for the best route to go from Charlotte, North Carolina to Lancaster, Pennsylvania.

Enlarge the route map Charlotte, North Carolina - Lancaster, Pennsylvania

Driving directions from Charlotte, North Carolina to Lancaster, Pennsylvania

I 77 $north, I 81 $north

515.0 mi7 hours 58 mins

Head south on East Trade Street 300 feet
Make a U-turn and continue on East Trade Street 0.4 mi
Go straight onto East Trade Street 1.0 mi
Turn right 0.3 mi
Merge left onto I 77 N 72.9 mi
Keep right onto I 77 N 54.1 mi
Take the ramp towards I 81 North: Roanoke 0.5 mi
Merge left towards I 81 North: Roanoke 12.0 mi
Continue onto I 81 N 102.5 mi
Continue onto I 64 E 224.4 mi
Take the ramp towards PA 581 East 0.5 mi
Continue onto American Ex-Prisoners of War Memorial Highway (PA 581 E) 6.9 mi
Continue towards I 83 North: Harrisburg 0.3 mi
Merge left onto Veterans of Foreign Wars of the United States Memorial Highway (I 83 N) 4.4 mi
Take exit 46A towards I 283 South: Airport 0.4 mi
Merge left onto I 283 S 2.5 mi
Take the ramp towards PA 283 East: Harrisburg International Airport 700 feet
Merge left onto PA 283 E 28.9 mi
Merge left onto US 30 700 feet
Take the ramp towards PA 501 0.2 mi
Go straight onto Chester Road 0.2 mi
Turn right onto Lititz Pike (US 222) 1.1 mi
Continue onto North Duke Street (US 222) 1.1 mi
Turn left onto East Mifflin Street 600 feet
Turn left onto South Lime Street (US 222) 200 feet
You have arrived at your destination

Print directions
Charlotte, North Carolina - Lancaster, Pennsylvania

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.