How to get from Charlottesville, VA to Charleston, SC

Discover, print or download the driving directions for the best route to go from Charlottesville, VA to Charleston, SC.

Enlarge the route map Charlottesville, VA - Charleston, SC

Driving directions from Charlottesville, VA to Charleston, SC

I 64 $east, I 95 $south

493.4 mi7 hours 31 mins

Head southeast on High Street East (US 250 Business) 0.2 mi
Turn left onto East High Street (US 250 Business) 0.9 mi
Turn right onto Long Street (US 250) 300 feet
Continue onto Richmond Road (US 250) 2.0 mi
Turn left towards I 64 East 0.3 mi
Merge left onto I 64 E 53.8 mi
Continue onto I 64 W 400 feet
Continue onto I 64 E 41.7 mi
Continue towards Rocky Mount 340.5 mi
Take the ramp towards I 26 East: Charleston 0.3 mi
Merge left onto I 26 E 51.9 mi
Take the ramp on the left towards Visitor Center 0.4 mi
Turn right onto Meeting Street (US 52) 1.2 mi
You have arrived at your destination

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Charlottesville, VA - Charleston, SC

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