I 64 $west, Dwight D. Eisenhower Highway
1,599.8 mi23 hours 40 mins
| Head west on High Street East (US 250 Business) | 0.3 mi | |
| Turn right onto Preston Avenue (US 250 Business) | 200 feet | |
| Turn left onto Ridge McIntire Road | 0.2 mi | |
| Continue onto Ridge Street | 0.4 mi | |
| Continue onto 5th Street Southwest | 1.6 mi | |
| Take the ramp on the right towards VA 631: 5th Street | 0.3 mi | |
| Merge left onto I 64 W | 32.1 mi | |
| Keep left towards I 64 West: Lexington | 30.5 mi | |
| Take the ramp towards I 64 West: Lexington | 120.7 mi | |
| Keep right onto I 64 W | 0.4 mi | |
| Merge left onto West Virginia Turnpike (I 64 W) | 61.0 mi | |
| Keep left towards I 64 West: Huntington | 168.2 mi | |
| Keep right towards I 64 West: Louisville | 6.9 mi | |
| Keep left towards I 64 West: Frankfort | 250.3 mi | |
| Keep right towards I 57 North | 4.6 mi | |
| Take the ramp on the left towards I 64 West: Saint Louis | 70.7 mi | |
| Take the ramp towards I 70 West: Kansas City | 0.7 mi | |
| Merge right onto I 70 W | 248.8 mi | |
| Keep left towards I 670 West: Topeka | 3.9 mi | |
| Continue onto I 70 | 1.0 mi | |
| Keep left onto Kansas Turnpike (I 70) | 52.6 mi | |
| Keep right towards I-70 West | 11.6 mi | |
| Keep left onto Dwight D. Eisenhower Highway (I 70) | 348.0 mi | |
| Continue onto I 70 | 7.2 mi | |
| Continue onto I 70 W | 169.4 mi | |
| Keep left onto I 70 W | 4.4 mi | |
| Take exit 275B towards CO 265 | 0.2 mi | |
| Make a sharp left onto Brighton Boulevard (CO 265) | 700 feet | |
| Keep left onto Brighton Boulevard | 1.5 mi | |
| Continue onto Broadway | 1.3 mi | |
| Turn right onto Tremont Place | 0.4 mi | |
| Turn left onto West Colfax Avenue (I 70 Bus) | 300 feet | |
| You have arrived at your destination |
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Charlottesville, Virginia - Denver, Colorado