Ronald Reagan Memorial Tollway, I 80
504.9 mi7 hours 43 mins
| Head south on North LaSalle Street | 0.3 mi | |
| Turn right onto West Adams Street | 400 feet | |
| Turn left onto South Wells Street | 0.3 mi | |
| Turn right onto West Ida B. Wells Drive | 600 feet | |
| Continue onto Eisenhower Expressway | 13.9 mi | |
| Keep left towards I 88 West Toll: Aurora | 1.9 mi | |
| Keep left onto Ronald Reagan Memorial Tollway (I 88 W) | 94.4 mi | |
| Continue onto Ronald Reagan Memorial Highway (I 88 W) | 38.9 mi | |
| Continue onto I 88 W | 4.6 mi | |
| Take the ramp towards I 80: Des Moines | 0.4 mi | |
| Keep right at the fork | 0.7 mi | |
| Merge left onto I 80 | 185.4 mi | |
| Take the ramp towards I 80 West: Council Bluffs | 118.9 mi | |
| Keep left towards I 80 West: Council Bluffs | 18.0 mi | |
| Take the ramp towards NE 50: Springfield | 0.6 mi | |
| Turn left onto State Highway 50 (NE 50) | 10.8 mi | |
| Continue onto Highway 50 (NE 50) | 0.3 mi | |
| Turn left onto Walnut Street | 0.7 mi | |
| Continue left onto Koop Avenue (NE 66) | 0.2 mi | |
| Continue onto Koop Anvenue (NE 66) | 700 feet | |
| Continue onto Highway 66 (NE 66) | 12.7 mi | |
| Continue onto Old Highway 34 | 700 feet | |
| Enter the roundabout and take the 3rd exit onto 8th Avenue | 300 feet | |
| Exit the roundabout onto 8th Avenue | 0.6 mi | |
| Turn left onto Chicago Avenue | 0.7 mi | |
| Turn left onto South 6th Street | 400 feet | |
| Turn right onto Main Street | 300 feet | |
| Turn left onto North 5th Street | 0 feet | |
| You have arrived at your destination |
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Chicago, Illinois - Plattsmouth, Nebraska