I 81 $north, I 66 $east
437.5 mi6 hours 51 mins
| Head east on Main Street (SR 346) | 0 feet | |
| Turn right onto South Central Avenue | 0.2 mi | |
| Make a slight right to stay on South Central Avenue | 1,000 feet | |
| Turn left onto Lee Highway (US 11W) | 5.3 mi | |
| Continue onto West Stone Drive (US 11W) | 21.7 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 81 N | 301.1 mi | |
| Take the ramp towards I 66 East: Front Royal | 0.4 mi | |
| Continue onto I 66 E | 74.2 mi | |
| Keep left towards I 66 East: Washington | 1,000 feet | |
| Continue onto Theodore Roosevelt Memorial Bridge (I 66 E) | 0.8 mi | |
| Take the ramp towards E Street | 0.2 mi | |
| Continue onto E Street Expressway | 0.3 mi | |
| Continue onto E Street Northwest | 0.3 mi | |
| Turn left onto 17th Street Northwest | 0.3 mi | |
| Turn right onto H Street Northwest | 0.4 mi | |
| Keep left onto H Street Northwest | 300 feet | |
| Turn left onto New York Avenue Northwest | 0.4 mi | |
| Continue onto K Street Northwest | 600 feet | |
| Turn left onto 7th Street Northwest | 300 feet | |
| Turn right onto New York Avenue Northwest | 4.5 mi | |
| Continue onto Baltimore-Washington Parkway (US 50) | 0.3 mi | |
| Continue towards US 50 East: Annapolis | 24.1 mi | |
| Take the ramp towards MD 70: Rowe Boulevard | 0.2 mi | |
| Keep right at the fork | 0.3 mi | |
| Go straight onto Roscoe Rowe Boulevard (MD 70 S) | 1.1 mi | |
| Keep right onto Roscoe Rowe Boulevard | 700 feet | |
| Turn left onto Northwest Street | 800 feet | |
| Enter Church Circle and take the 4th exit onto Duke of Gloucester Street | 400 feet | |
| Exit the roundabout onto Duke of Gloucester Street | 900 feet | |
| You have arrived at your destination |
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Church Hill, Tennessee - Annapolis, Maryland