How to get from Cincinnati, OH to Louisville, KY

Discover, print or download the driving directions for the best route to go from Cincinnati, OH to Louisville, KY.

Enlarge the route map Cincinnati, OH - Louisville, KY

Driving directions from Cincinnati, OH to Louisville, KY

I 71 $south; I 75 $south, I 71 $south

100.2 mi1 hour 35 mins

Head southwest on Gilbert Avenue (US 22) 0.2 mi
Turn right onto Broadway Street 400 feet
Turn left onto East 9th Street 1.0 mi
Take the ramp on the left towards I 71: Louisville 0.2 mi
Merge left onto Mill Creek Expressway (I 75 S) 0.6 mi
Continue onto Brent Spence Bridge (I 71 S) 18.8 mi
Take the ramp towards I 71 South: Louisville 76.8 mi
Take the ramp towards I 64 West: Saint Louis 0.5 mi
Merge left onto I 64 W 1.5 mi
Take the ramp towards 9th Street 0.5 mi
Keep right at the fork 300 feet
Go straight onto West Jefferson Street 300 feet
You have arrived at your destination

Print directions
Cincinnati, OH - Louisville, KY

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.