US 19; US 98; US 27 Alternate, FL 20
339.1 mi6 hours 18 mins
| Head east on Cleveland Street | 0.5 mi | |
| Turn left onto North Missouri Avenue | 900 feet | |
| Turn right onto Drew Street (FL 590) | 2.1 mi | |
| Make a slight left onto Northeast Coachman Road (FL 590) | 0.5 mi | |
| Turn left onto Belcher Road (CR 501) | 1.2 mi | |
| Continue onto North Belcher Road (CR 501) | 1.3 mi | |
| Keep right onto Countryside Boulevard | 0.6 mi | |
| Go straight | 300 feet | |
| Go straight onto US 19 Northbound Frontage Road | 0.4 mi | |
| Take the ramp | 0.2 mi | |
| Merge left onto US 19 N | 12.6 mi | |
| Continue onto US 19 | 165.4 mi | |
| Turn left onto Hampton Springs Avenue (US 98) | 1.4 mi | |
| Go straight onto US 98 | 37.2 mi | |
| Turn right onto Bloxham Cutoff Road (FL 267) | 30.8 mi | |
| Turn left onto Jackson Bluff Road (FL 20) | 0.7 mi | |
| Continue onto Blountstown Highway (FL 20) | 49.2 mi | |
| Turn left onto US 231 | 22.6 mi | |
| Turn right | 300 feet | |
| Go straight onto East 23rd Street (FL 368) | 5.4 mi | |
| Turn right onto US 98 | 2.2 mi | |
| Make a slight left onto Front Beach Road (FL 30) | 4.6 mi | |
| You have arrived at your destination |
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Clearwater, Florida - Panama City Beach, Florida