I 70 $east; US 40 $east, I 24 $east
572.8 mi8 hours 45 mins
| Head north on North Providence Road (MO 163) | 1.1 mi | |
| Take the ramp on the right | 900 feet | |
| Merge left onto I 70 E | 96.5 mi | |
| Keep left onto I 70 E | 20.7 mi | |
| Keep right onto I 70 E | 8.0 mi | |
| Take the ramp towards I 64 East: Louisville | 0.6 mi | |
| Merge left onto I 64 E | 70.1 mi | |
| Keep right towards I 57 South | 13.0 mi | |
| Continue onto I 57 S | 38.8 mi | |
| Take the ramp towards I 24 East: Nashville | 1.4 mi | |
| Continue onto I 24 E | 175.1 mi | |
| Keep right towards I 24 East: Nashville | 2.3 mi | |
| Keep left towards I 24 East: Chattanooga | 2.8 mi | |
| Keep left towards I 40 East: Knoxville | 2.1 mi | |
| Keep right towards I 24 East: Chattanooga | 0.8 mi | |
| Keep left onto I 24 E | 126.1 mi | |
| Take the ramp towards US 27 North: Downtown Chattanooga | 700 feet | |
| Keep left at the fork | 0.3 mi | |
| Continue onto US 27 S | 0.7 mi | |
| Take exit 1A towards M L King Boulevard | 0.2 mi | |
| Turn right onto W Martin Luther King Boulevard | 700 feet | |
| Continue onto East Martin Luther King Boulevard (SR 8) | 700 feet | |
| Turn left onto Georgia Avenue | 0.5 mi | |
| Turn right onto East 4th Street | 0.4 mi | |
| Make a slight left | 600 feet | |
| Go straight onto Riverside Drive | 1.3 mi | |
| Turn right onto Wilcox Boulevard | 0.9 mi | |
| Turn left onto Dodson Avenue (SR 17) | 0.8 mi | |
| Turn right onto Glass Street (SR 17) | 0.7 mi | |
| Turn left onto Campbell Street (SR 17) | 0.6 mi | |
| Continue onto Bonny Oaks Drive (SR 17) | 6.2 mi | |
| Make a U-turn and continue on TN 58 | 300 feet | |
| You have arrived at your destination, on the left |
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Columbia, Missouri - Harrison, Tennessee