Dwight D. Eisenhower Highway, I 40
1,720.3 mi1 day 1 hour 23 mins
| Head east on West Colfax Avenue (I 70 Bus) | 100 feet | |
| Turn left onto Court Place | 0.3 mi | |
| Make a slight right onto East 17th Avenue | 400 feet | |
| Turn left onto Lincoln Street | 0.3 mi | |
| Continue left onto 20th Street | 500 feet | |
| Turn right onto Broadway | 1.0 mi | |
| Continue onto Brighton Boulevard | 1.5 mi | |
| Take the ramp on the right towards I 70 East | 0.3 mi | |
| Merge left onto I 70 E | 1.0 mi | |
| Keep left onto I 70 E | 172.7 mi | |
| Continue onto I 70 | 354.4 mi | |
| Keep left onto Dwight D. Eisenhower Highway (I 70) | 10.5 mi | |
| Keep left towards I-70 East | 2.1 mi | |
| Merge right onto Kansas Turnpike (I 70) | 12.7 mi | |
| Take the ramp towards KS 10: Lecompton | 0.4 mi | |
| Keep right at the fork | 400 feet | |
| Merge left onto South Lawrence Trafficway (KS 10) | 36.4 mi | |
| Keep left towards I 435 East | 0.2 mi | |
| Merge left onto I 435 | 12.2 mi | |
| Keep left towards I 435 North: Des Moines | 9.1 mi | |
| Take exit 63B towards I 70 East: Saint Louis | 0.8 mi | |
| Keep left towards I 70 East: Saint Louis | 500 feet | |
| Merge left onto Truman/Eisenhower Presidential Highway (I 70 E) | 92.2 mi | |
| Keep left onto I 70 E | 142.4 mi | |
| Keep right onto I 70 E | 8.0 mi | |
| Take the ramp towards I 64 East: Louisville | 0.6 mi | |
| Merge left onto I 64 E | 70.1 mi | |
| Keep right towards I 57 South | 13.0 mi | |
| Continue onto I 57 S | 38.8 mi | |
| Take the ramp towards I 24 East: Nashville | 1.4 mi | |
| Continue onto I 24 E | 175.1 mi | |
| Keep right towards I 24 East: Nashville | 2.3 mi | |
| Keep left towards I 24 East: Chattanooga | 2.8 mi | |
| Keep left towards I 40 East: Knoxville | 210.2 mi | |
| Keep right towards I 40 East: Asheville | 76.3 mi | |
| Take the ramp towards I 26 East: Hendersonville | 13.3 mi | |
| Continue onto I 26 E | 134.6 mi | |
| Keep right towards Charleston | 104.4 mi | |
| Take the ramp towards I 526: Mount Pleasant | 0.2 mi | |
| Keep left towards I 526 East: Mount Pleasant | 0.3 mi | |
| Keep right towards I 526 East: Mount Pleasant | 0.2 mi | |
| Merge left onto Mark Clark Expressway (I 526 E) | 11.7 mi | |
| Take the ramp towards US 17 North: Georgetown | 0.5 mi | |
| Keep right at the fork | 0.2 mi | |
| Keep left at the fork | 200 feet | |
| Turn left onto US 17 | 1.4 mi | |
| Turn right onto Isle of Palms Connector (SC 517) | 3.9 mi | |
| Turn left onto Palm Boulevard | 0.3 mi | |
| You have arrived at your destination |
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Denver, Colorado - Isle of Palms, South Carolina