US 281 $north, I 35 $north
1,013.5 mi15 hours 35 mins
| Head north on Salinas Boulevard (FM 493) | 0.6 mi | |
| Turn left onto West Expressway 83 | 0.4 mi | |
| Take the ramp on the left | 1,000 feet | |
| Merge left onto I 2 W | 7.8 mi | |
| Take the ramp towards I 69C North: Edinburg | 0.8 mi | |
| Continue onto I 69C N | 18.8 mi | |
| Continue onto US 281 N | 37.6 mi | |
| Turn right | 0.5 mi | |
| Turn left | 1.0 mi | |
| Turn right | 0.3 mi | |
| Turn left | 1.1 mi | |
| Turn right | 1.8 mi | |
| Turn left | 2.6 mi | |
| Turn right onto US 281 N | 10.6 mi | |
| Continue onto South Railroad Street | 1.5 mi | |
| Take the ramp | 900 feet | |
| Continue onto Fallifurias Expressway (US 281 N) | 90.4 mi | |
| Take the ramp onto US 281 N | 61.2 mi | |
| Take the ramp towards I 410 | 800 feet | |
| Keep right towards I 410 North | 0.5 mi | |
| Merge left onto Connally Loop (I 410 N) | 7.0 mi | |
| Take the ramp towards I 10: Downtown San Antonio | 600 feet | |
| Keep right towards I 10 East: Houston | 0.4 mi | |
| Keep left towards I 10 East: Houston | 900 feet | |
| Merge left onto 90th Infantry Division Highway (I 10) | 21.7 mi | |
| Continue onto I 10 | 10.9 mi | |
| Keep right towards TX Toll 130 North: Austin | 46.6 mi | |
| Keep left onto Pickle Parkway (TX 45 Toll N) | 7.8 mi | |
| Keep right onto Pickle Parkway (TX 45 Toll) | 11.2 mi | |
| Keep left onto Pickle Parkway (TX 45 Toll N) | 12.3 mi | |
| Keep right onto TX 130 Toll N | 9.8 mi | |
| Merge left onto I 35 N | 37.6 mi | |
| Keep left onto I 35 N | 32.3 mi | |
| Keep left onto Jack Kultgen Freeway (I 35 N) | 17.9 mi | |
| Keep left onto I 35 N | 16.8 mi | |
| Keep left towards I 35W: Fort Worth | 57.1 mi | |
| Take the ramp on the left towards I 35W North Express: Express Lanes | 500 feet | |
| Merge left onto I 35W TEXpress | 4.5 mi | |
| Merge left onto North Freeway (I 35W N) | 24.6 mi | |
| Continue onto I 35 N | 87.1 mi | |
| Take exit 51 towards US 77: Turner Falls Area | 0.2 mi | |
| Keep right at the fork | 200 feet | |
| Go straight onto US 77 N | 3.5 mi | |
| Turn right onto West Main Street (OK 7 E) | 0.4 mi | |
| Turn left onto North 3rd Street (US 77 N) | 10.3 mi | |
| Turn left onto West Kerr Boulevard (US 77 N) | 2.0 mi | |
| Turn left onto OK 29 | 1.1 mi | |
| Take the ramp on the right | 0.3 mi | |
| Continue onto Director Steven Stokes Memorial Highway (I 35 N) | 8.4 mi | |
| Continue onto World War I Veterans Memorial Highway (I 35 N) | 32.6 mi | |
| Continue onto McCall Bridge (OK 9 E) | 0.7 mi | |
| Keep left onto World War I Veterans Memorial Highway (I 35 N) | 0.9 mi | |
| Continue onto Doctor James E. and Representative Mina M. Hibdon Memorial Highway (I 35 N) | 5.7 mi | |
| Continue onto Helen Cole Memorial Highway (I 35 N) | 6.7 mi | |
| Continue onto World War I Veterans Memorial Highway (I 35 N) | 5.2 mi | |
| Keep right towards I 35 North: Wichita | 0.3 mi | |
| Merge left onto Crosstown Expressway (I 35 N) | 1.0 mi | |
| Keep right towards I 35 North: Wichita | 2.4 mi | |
| Continue onto Honorable Hannah Diggs Atkins, Secretary of State, Memorial Highway (I 35 N) | 2.9 mi | |
| Continue towards I 35 North | 5.4 mi | |
| Continue onto Shannon Miller Parkway (I 35 N) | 4.1 mi | |
| Continue onto World War II Veterans Memorial Highway (I 35 N) | 93.4 mi | |
| Continue onto Kansas Turnpike (I 35 N) | 176.9 mi | |
| Take the ramp | 0.5 mi | |
| Continue onto I 470 E | 400 feet | |
| Take the ramp towards Topeka Boulevard | 0.2 mi | |
| Keep left at the fork | 200 feet | |
| Turn left onto Southwest Topeka Boulevard | 3.0 mi | |
| Turn right onto Southwest 17th Street | 0.2 mi | |
| Turn left onto South Kansas Avenue | 1.0 mi | |
| Turn right onto Southeast 7th Street | 900 feet | |
| Turn right onto Southeast Monroe Street | 0 feet | |
| You have arrived at your destination |
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Donna, Texas - Topeka, Kansas