How to get from Durham, North Carolina to Charleston, South Carolina

Discover, print or download the driving directions for the best route to go from Durham, North Carolina to Charleston, South Carolina.

Enlarge the route map Durham, North Carolina - Charleston, South Carolina

Driving directions from Durham, North Carolina to Charleston, South Carolina

I 95 $south, I 26 $east

304.6 mi4 hours 39 mins

Head southeast on Holloway Street (US 70 Business) 0.3 mi
Turn right onto North Elizabeth Street 0.3 mi
Continue onto Fayetteville Road 0.4 mi
Take the ramp on the left 800 feet
Merge left onto Durham Freeway (NC 147 S) 6.6 mi
Take the ramp on the left towards I 40 East 0.8 mi
Merge right onto I 40 8.7 mi
Keep left onto I 40 12.6 mi
Keep right towards I 40 East: Wilmington 26.5 mi
Take the ramp towards I 95 North: Benson 0.6 mi
Merge left onto I 95 S 193.7 mi
Take the ramp towards I 26 East: Charleston 0.3 mi
Merge left onto I 26 E 51.9 mi
Take the ramp on the left towards Visitor Center 0.4 mi
Turn right onto Meeting Street (US 52) 1.2 mi
You have arrived at your destination

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Durham, North Carolina - Charleston, South Carolina

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