I 74 $east; US 421 $south, I 75 $south
225.7 mi3 hours 50 mins
| Head south | 0 feet | |
| Turn left onto East 116th Street | 0.3 mi | |
| Take the ramp on the right | 0.4 mi | |
| Merge left onto I 69 S | 4.0 mi | |
| Take exit 200 towards I-465 | 0.2 mi | |
| Keep left towards I-465 South | 1.0 mi | |
| Merge left onto I 465 E | 7.9 mi | |
| Continue onto I 465 S | 1.3 mi | |
| Continue onto Interstate 465 (I 465 S) | 0.7 mi | |
| Continue onto I 465 S | 1.2 mi | |
| Take exit 49 towards I 74 East: Cincinnati | 700 feet | |
| Keep left towards I 74 East: Cincinnati | 70.4 mi | |
| Take exit 164 towards SR 1: Saint Leon | 0.2 mi | |
| Turn right onto SR 1 | 14.2 mi | |
| Turn right to stay on SR 1 | 600 feet | |
| Turn left onto Belleview Drive (SR 1) | 0.3 mi | |
| Continue towards I 275: Ohio | 0.4 mi | |
| Keep right towards I 275 South: Kentucky | 0.5 mi | |
| Merge left onto I 275 S | 0.6 mi | |
| Continue onto Carroll Lee Cropper Bridge (I 275 E) | 13.5 mi | |
| Take exit 84 towards I 71: Cincinnati | 0.3 mi | |
| Keep right towards I 71 South: Lexington | 0.7 mi | |
| Keep left towards I 71 South: Lexington | 0.3 mi | |
| Keep left at the fork | 0.7 mi | |
| Merge left onto I 71 S | 72.0 mi | |
| Take exit 111 on the left towards I 64 East: Winchester | 16.6 mi | |
| Keep right towards Mountain Parkway east | 16.1 mi | |
| Take the ramp | 0.2 mi | |
| Keep left at the fork | 100 feet | |
| Turn left onto Winchester Road (KY 15) | 600 feet | |
| Turn left onto Main Street (KY 15) | 1.2 mi | |
| You have arrived at your destination |
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Fishers, Indiana - Clay City, Kentucky