I 74 $east; IL 110 $west, 19
351.1 mi6 hours 22 mins
| Head northwest on South Walnut Avenue | 100 feet | |
| Turn left onto East Main Street | 200 feet | |
| Turn left onto 1st Avenue (IL 26) | 8.8 mi | |
| Turn left to stay on US 52 | 6.4 mi | |
| Turn left to stay on South Il Route 26 | 300 feet | |
| Continue onto US 52 | 9.3 mi | |
| Turn left | 0.2 mi | |
| Keep right at the fork | 0.4 mi | |
| Merge left onto Ronald Reagan Memorial Tollway (I 88 W) | 9.5 mi | |
| Continue onto Ronald Reagan Memorial Highway (I 88 W) | 38.9 mi | |
| Continue onto I 88 W | 5.4 mi | |
| Take the ramp towards I 80: Peoria | 38.5 mi | |
| Take exit 46A towards US 34 West: Monmouth | 16.9 mi | |
| Continue onto US 34 | 35.6 mi | |
| Turn right onto West Calhoun Street (US 136) | 800 feet | |
| Continue slightly left onto North Johnson Street (US 136) | 600 feet | |
| Turn right onto West Jackson Street (US 136) | 3.8 mi | |
| Turn left onto IL 110 | 53.5 mi | |
| Continue onto IL 110 S | 1.3 mi | |
| Continue onto I 172 S | 19.1 mi | |
| Continue onto I 72 W | 4.3 mi | |
| Continue onto V.F.W. Memorial Highway (I 72 W) | 1.4 mi | |
| Take the ramp towards US 61: New London | 700 feet | |
| Keep left towards US 61 South: New London | 300 feet | |
| Make a slight left onto McMasters Avenue (US 61) | 600 feet | |
| Continue onto Avenue of the Saints (US 61) | 0.7 mi | |
| Continue onto McMasters Avenue (US 61 S) | 1.6 mi | |
| Continue onto Avenue of the Saints (US 61 S) | 7.9 mi | |
| Take the ramp | 0.2 mi | |
| Turn right onto 19 | 35.0 mi | |
| Turn right to stay on US 54 | 10.5 mi | |
| Turn left towards US 54 West: Jefferson City | 18.1 mi | |
| Take the ramp towards I 70 West: Columbia | 0.2 mi | |
| Merge left onto I 70 W | 21.0 mi | |
| Take the ramp towards MO 163: Downtown | 600 feet | |
| Keep left at the fork | 200 feet | |
| Turn left onto North Providence Road (MO 163) | 1.6 mi | |
| Turn left onto East Stewart Road | 0.2 mi | |
| Turn right onto South 6th Street | 100 feet | |
| Turn left | 200 feet | |
| You have arrived at your destination, straight ahead |
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Forreston, IL, USA - Columbia, MO, USA