I 81 $north, I 77 $south
280.1 mi4 hours 45 mins
| Head southwest on State Route 810 | 0 feet | |
| Turn left onto SR 65 | 0.5 mi | |
| Turn right onto SR 72 | 10.7 mi | |
| Turn right onto Nickelsville Road (SR 71) | 700 feet | |
| Continue onto East Jackson Street (SR 71) | 0.8 mi | |
| Turn left onto Jones Street | 0.3 mi | |
| Turn left onto Kane Street (US 23 Business) | 0.2 mi | |
| Turn left onto US 23 | 1.0 mi | |
| Turn left onto US 58 | 0.3 mi | |
| Continue onto SR 224 | 4.6 mi | |
| Turn left onto Bloomingdale Pike | 5.1 mi | |
| Turn right onto Ollis Bowers Hill Road | 400 feet | |
| Turn left onto East Stone Drive (US 11W) | 9.7 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto I 81 N | 82.1 mi | |
| Take the ramp towards I 77 South: Charlotte NC | 37.3 mi | |
| Take the ramp on the left towards I 74 East: Mount Airy | 12.7 mi | |
| Continue onto Pilot Mountain Parkway (US 52 S) | 30.7 mi | |
| Take the ramp towards I 40 Business East: Kernersville | 800 feet | |
| Merge left onto I 40 Business E | 2.0 mi | |
| Continue onto I 40 Business E | 11.2 mi | |
| Merge left onto I 40 | 4.8 mi | |
| Keep right onto I 40 | 7.8 mi | |
| Merge right onto I 40 | 1.8 mi | |
| Keep left onto I 40 | 34.5 mi | |
| Take the ramp | 0.3 mi | |
| Keep right at the fork | 0.2 mi | |
| Keep left at the fork | 100 feet | |
| Turn left onto I 85 US 70 Connector (NC 86 Truck) | 3.7 mi | |
| Make a sharp left onto NC 86 | 0.4 mi | |
| Turn right onto NC 57 | 14.6 mi | |
| Turn right onto Durham Road (US 501) | 0.6 mi | |
| Continue onto Roxboro Road (US 501) | 1.1 mi | |
| Continue onto Roxboro Street (US 501) | 0.4 mi | |
| You have arrived at your destination | 0 feet |
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Fort Blackmore, Virginia - Rougemont, North Carolina