I 95 $south, John F. Kennedy Memorial Highway
586.9 mi9 hours 11 mins
| Head northwest on Colonial Drive | 200 feet | |
| Turn left onto Foulk Road | 6.8 mi | |
| Take the ramp onto DE 261 | 0.2 mi | |
| Turn left onto Concord Pike (US 202) | 0.6 mi | |
| Take the ramp towards I 95 South: Del Mem Bridge | 0.3 mi | |
| Merge right onto I 95 S | 57.8 mi | |
| Keep right onto John F. Kennedy Memorial Highway (I 95 S) | 6.5 mi | |
| Keep right towards I 895 South: Annapolis | 5.0 mi | |
| Continue onto Baltimore Harbor Tunnel (I 895 S) | 1.4 mi | |
| Continue onto Harbor Tunnel Thruway (I 895 S) | 2.1 mi | |
| Continue onto Harbor Tunnel Throughway (I 895 S) | 0.5 mi | |
| Keep left onto Harbor Tunnel Throughway (I 895 S) | 0.5 mi | |
| Continue onto Harbor Tunnel Thruway (I 895 S) | 1.3 mi | |
| Take the ramp towards MD 295 South | 0.4 mi | |
| Merge left onto Baltimore-Washington Parkway (MD 295 S) | 27.6 mi | |
| Continue onto Kenilworth Avenue Freeway (MD 201) | 2.2 mi | |
| Continue onto Anacostia Freeway (DC 295 S) | 2.1 mi | |
| Take exit 1B-C towards I 695 West: Downtown | 0.3 mi | |
| Keep right towards I 695 West: Downtown | 600 feet | |
| Continue onto 11th Street Bridge (I 695 W) | 800 feet | |
| Continue onto Southeast Freeway (I 695 W) | 1.7 mi | |
| Continue onto Southwest Freeway (I 395 S) | 0.7 mi | |
| Continue onto Francis Case Memorial Bridge (I 395 S) | 0.3 mi | |
| Keep right onto I 395 S | 1.2 mi | |
| Keep right towards I 395 South | 9.0 mi | |
| Continue towards I 95 South: Richmond | 59.4 mi | |
| Continue onto I 95 S | 25.7 mi | |
| Take the ramp on the left towards I 295 South: Rocky Mount NC | 1.8 mi | |
| Merge right onto I 295 | 42.4 mi | |
| Merge right towards I 95 South: Emporia | 328.3 mi | |
| Take the ramp towards SC 6: Santee | 0.2 mi | |
| Keep right towards SC 6 West: Santee | 200 feet | |
| Make a slight right onto Old Number Six Highway (SC 6) | 0.2 mi | |
| Turn left onto Bass Drive | 400 feet | |
| You have arrived at your destination |
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Garnet Valley, Pennsylvania - Santee, South Carolina