I 40, I 55 $south
652.9 mi10 hours 43 mins
| Head west on State Highway 126 (37) | 11.3 mi | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto I 49 S | 16.5 mi | |
| Take exit 53 towards I 49 Business: Webb City | 800 feet | |
| Turn right onto I 49 Business | 1.4 mi | |
| Keep left onto I 49 Business | 5.3 mi | |
| Keep left towards MO 249 South: Joplin | 6.2 mi | |
| Continue onto I 49 S | 122.0 mi | |
| Keep left towards I 40 East: Alma | 0.6 mi | |
| Merge left onto I 40 | 141.9 mi | |
| Keep right onto I 40 | 124.9 mi | |
| Take the ramp towards I 55 South: Memphis | 0.5 mi | |
| Keep left onto I 55 E | 1.2 mi | |
| Continue onto I 55 | 3.5 mi | |
| Take the ramp towards I 55 South: Jackson Mississippi | 6.0 mi | |
| Continue onto I 55 S | 122.4 mi | |
| Take the ramp | 0.3 mi | |
| Turn left onto MS 35 | 24.4 mi | |
| Turn left onto East Jefferson Street | 700 feet | |
| Turn right onto South Huntington Street | 1.4 mi | |
| Make a slight left onto MS 731 | 200 feet | |
| Turn right onto Veterans Memorial Drive (MS 19) | 1.1 mi | |
| Turn left onto MS 14 | 3.4 mi | |
| Keep right onto MS 14 | 10.8 mi | |
| Turn left onto MS 19 | 19.4 mi | |
| Turn right onto MS 19 | 0.2 mi | |
| Turn left to stay on MS 15 | 18.7 mi | |
| Turn left onto MS 494 | 8.9 mi | |
| You have arrived at your destination, on the right |
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Golden City, Missouri - Purdue, Mississippi