I 80, US 22 $east; US 322 $east
265.9 mi4 hours 33 mins
| Head southeast on West Main Street (PA 58) | 300 feet | |
| Turn left onto South Broad Street (PA 173 N) | 3.0 mi | |
| Continue onto Sandy Lake Road (PA 173) | 0.3 mi | |
| Take the ramp on the right | 0.5 mi | |
| Merge left onto I 80 | 98.1 mi | |
| Take the ramp towards PA 970 to US 322: Woodland | 0.3 mi | |
| Go straight onto Shawville Highway (PA 970) | 1.4 mi | |
| Turn left onto Woodland Bigler Highway (US 322) | 2.8 mi | |
| Continue onto Philipsburg Bigler Highway (US 322) | 7.1 mi | |
| Continue onto North Front Street (US 322) | 0.3 mi | |
| Continue onto North Centre Street (US 322) | 800 feet | |
| Turn left onto Railroad Street (US 322) | 1.0 mi | |
| Continue onto Twenty-Eighth Division Highway (US 322) | 6.5 mi | |
| Continue onto Upper Flat Rock Road (US 322) | 1.6 mi | |
| Continue onto Flat Rock Road (US 322) | 1.5 mi | |
| Continue onto 28th Division Highway (US 322 E) | 12.8 mi | |
| Keep right towards US 322 East: The Pennsylvania State University | 6.3 mi | |
| Continue onto General Potter Highway (US 322) | 82.0 mi | |
| Turn left onto Paxton Street | 0.2 mi | |
| Turn right onto South 13th Street | 300 feet | |
| Take the ramp on the right towards I 83 South: York | 0.2 mi | |
| Merge left onto Veterans of Foreign Wars of the United States Memorial Highway (I 83 S) | 1.5 mi | |
| Keep right towards I 83 South: York | 23.7 mi | |
| Take the ramp towards PA 124 | 800 feet | |
| Turn left onto Mount Rose Avenue (PA 124) | 1.0 mi | |
| Continue onto East Prospect Road (PA 124) | 0.3 mi | |
| Turn right onto Cape Horn Road (PA 24 S) | 0.7 mi | |
| Turn left onto Windsor Road | 4.5 mi | |
| Continue slightly right onto North Penn Street | 0.4 mi | |
| Continue onto Windsor Road | 1.0 mi | |
| Turn left onto Delta Road (PA 74) | 6.2 mi | |
| You have arrived at your destination |
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Grove City, Pennsylvania - Brogue, Pennsylvania