US 54, I 44 $west
277.5 mi4 hours 51 mins
| Head west on Broadway Extended | 0.4 mi | |
| Continue onto Saint Marys Avenue | 900 feet | |
| Turn left onto James Road | 800 feet | |
| Turn left onto Avenue of the Saints (US 61) | 800 feet | |
| Continue onto McMasters Avenue (US 61 S) | 1.6 mi | |
| Continue onto Avenue of the Saints (US 61 S) | 7.9 mi | |
| Take the ramp | 0.2 mi | |
| Turn right onto 19 | 35.0 mi | |
| Turn right to stay on US 54 | 10.5 mi | |
| Turn left towards US 54 West: Jefferson City | 47.8 mi | |
| Keep left towards US 54 West: Eldon | 57.9 mi | |
| Take the ramp on the right towards MO 5 South: Lebanon | 0.2 mi | |
| Merge left onto MO 5 S | 24.0 mi | |
| Turn left onto North Jefferson Avenue (MO 5) | 1.6 mi | |
| Take the ramp on the right towards I 44 West: Springfield | 700 feet | |
| Merge left onto I 44 W | 46.4 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto Schoolcraft Freeway (US 65 S) | 41.5 mi | |
| Take the ramp towards MO 248 | 1,000 feet | |
| Keep left towards Red Route East | 300 feet | |
| Go straight onto Branson Landing Boulevard (Red Route) | 0.6 mi | |
| Make a slight right onto Veterans Boulevard (Red Route) | 0.4 mi | |
| Continue onto US 65 Bus | 500 feet | |
| Make a sharp right onto West College Street | 100 feet | |
| Turn left onto South 2nd Street | 300 feet | |
| Turn left onto West Maddux Street | 100 feet | |
| You have arrived at your destination |
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Hannibal, Missouri - Branson, Missouri