How to get from Harrisonburg, Virginia to Charleston, South Carolina

Discover, print or download the driving directions for the best route to go from Harrisonburg, Virginia to Charleston, South Carolina.

Enlarge the route map Harrisonburg, Virginia - Charleston, South Carolina

Driving directions from Harrisonburg, Virginia to Charleston, South Carolina

I 77 $south, I 26 $east

502.1 mi7 hours 44 mins

Head west on West Wolfe Street 100 feet
Turn left onto North Liberty Street (US 11) 0.6 mi
Make a slight right onto South Main Street (US 11) 0.6 mi
Turn left onto Port Republic Road (VA 253) 0.5 mi
Take the ramp on the right 0.2 mi
Merge left onto I 81 S 164.2 mi
Take the ramp towards I 77 South: Charlotte NC 0.4 mi
Continue towards I 77 South: Charlotte NC 0.4 mi
Continue onto I 77 S 100.6 mi
Keep right onto I 77 S 109.4 mi
Keep left onto I 77 S 18.4 mi
Keep left towards I 26 South: Charleston 0.8 mi
Merge right onto I 26 E 104.3 mi
Take the ramp on the left towards Visitor Center 0.4 mi
Turn right onto Meeting Street (US 52) 1.2 mi
You have arrived at your destination

Print directions
Harrisonburg, Virginia - Charleston, South Carolina

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.