US 54, I 55 $north
478.6 mi7 hours 59 mins
| Head west on Center Street | 100 feet | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto US 54 | 42.2 mi | |
| Turn right onto East Liberty Street (US 54) | 10.3 mi | |
| Turn left onto US 54 | 8.1 mi | |
| Turn right to stay on US 54 | 55.5 mi | |
| Turn left onto US 54 | 5.1 mi | |
| Take the ramp on the right towards I 72 East: Springfield | 0.3 mi | |
| Merge left onto I 72 E | 83.5 mi | |
| Continue onto I 55 N | 13.1 mi | |
| Keep right towards I 55 North: Chicago | 29.3 mi | |
| Keep left towards I 55 North: Chicago | 67.9 mi | |
| Continue onto I-55 N | 5.7 mi | |
| Continue onto I 55 N | 20.3 mi | |
| Take exit 250A towards I 80 East: Indiana | 0.8 mi | |
| Merge left onto I 80 | 28.3 mi | |
| Keep right onto I 80 | 19.1 mi | |
| Take the ramp towards I 65 South: Indianapolis | 0.4 mi | |
| Keep left at the fork | 0.8 mi | |
| Merge left onto I 65 S | 5.5 mi | |
| Take the ramp | 0.5 mi | |
| Keep left at the fork | 200 feet | |
| Merge left onto East 81st Avenue (US 30 E) | 79.5 mi | |
| Take the ramp | 0.4 mi | |
| Turn right onto SR 15 | 1.8 mi | |
| You have arrived at your destination |
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Holts Summit, Missouri - Warsaw, Indiana