How to get from Key Largo, Florida to Jacksonville, Florida

Discover, print or download the driving directions for the best route to go from Key Largo, Florida to Jacksonville, Florida.

Enlarge the route map Key Largo, Florida - Jacksonville, Florida

Driving directions from Key Largo, Florida to Jacksonville, Florida

Florida's Turnpike, I 95 $north

399.3 mi6 hours 2 mins

Head southwest on Overseas Highway (US 1) 500 feet
Make a U-turn and continue on Overseas Highway (US 1) 2.5 mi
Continue onto Dixie Highway (US 1) 19.4 mi
Keep right onto Homestead Extension of Florida's Turnpike 17.3 mi
Keep left onto Homestead Extension of Florida's Turnpike 30.6 mi
Merge left onto Florida's Turnpike 16.4 mi
Keep right onto Florida's Turnpike 88.6 mi
Take the ramp towards FL 70: Fort Pierce 0.5 mi
Keep right at the fork 200 feet
Merge left onto Okeechobee Road (FL 70) 0.7 mi
Take the ramp towards I 95 North: Daytona Beach 0.3 mi
Merge left onto I 95 N 220.3 mi
Keep left towards Downtown 1.1 mi
Keep right at the fork 500 feet
Keep left at the fork 0.4 mi
Continue onto Main Street Bridge (US 1) 0.2 mi
Continue onto John T. Aslop Bridge (US 1) 400 feet
Keep left towards US 1 North 0.5 mi
Turn left onto Beaver Street (US 90) 300 feet
You have arrived at your destination

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Key Largo, Florida - Jacksonville, Florida

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