How to get from Key Largo, Florida to Tampa Bay

Discover, print or download the driving directions for the best route to go from Key Largo, Florida to Tampa Bay.

Enlarge the route map Key Largo, Florida - Tampa Bay

Driving directions from Key Largo, Florida to Tampa Bay

I 75 $north, Alligator Alley

311.1 mi4 hours 49 mins

	Head southwest on Overseas Highway (US 1)	500 feet
	Make a U-turn and continue on Overseas Highway (US 1)	2.5 mi
	Continue onto Dixie Highway (US 1)	19.4 mi
	Keep right onto Homestead Extension of Florida's Turnpike	17.3 mi
	Keep left onto Homestead Extension of Florida's Turnpike	21.5 mi
	Take the ramp towards I 75 North: Naples	1.1 mi
	Merge left onto I 75 N	11.2 mi
	Keep left towards Alligator Alley	211.0 mi
	Take the ramp towards I 275 North: Saint Petersburg	1.2 mi
	Continue onto I 275 N	22.1 mi
	Take the ramp towards 22nd Avenue North	1,000 feet
	Keep right towards 22nd Avenue North	200 feet
	Make a slight right onto 22nd Avenue North	1.9 mi
	Turn right onto Coffee Pot Boulevard Northeast	600 feet
	Turn left onto Snell Isle Boulevard Northeast	0.5 mi
	Turn right onto Snell Isle Boulevard Northeast	0.6 mi
	Turn right onto Cordova Boulevard Northeast	0.3 mi
	Turn left onto Brightwaters Boulevard Northeast	900 feet
	You have arrived at your destination

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Key Largo, Florida - Tampa Bay

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