I 90 $west, US 52
180.1 mi2 hours 55 mins
| Head northwest on Main Street | 200 feet | |
| Turn left onto 3rd Street South (US 53) | 0.3 mi | |
| Turn right onto Cass Street (US 14) | 1.4 mi | |
| Continue onto US 14 | 1.7 mi | |
| Turn right | 400 feet | |
| Continue onto US 14 | 2.0 mi | |
| Continue onto US 61 | 0.2 mi | |
| Keep left onto US 61 | 0.6 mi | |
| Merge right onto I 90 W | 4.1 mi | |
| Continue onto I 90 W | 52.7 mi | |
| Take the ramp towards US 52 | 0.3 mi | |
| Keep right at the fork | 1,000 feet | |
| Merge right onto US 52 N | 5.1 mi | |
| Keep left onto US 52 N | 30.2 mi | |
| Continue onto US 52 | 35.5 mi | |
| Take the ramp onto Clayton Avenue (US 52 N) | 0.4 mi | |
| Merge right onto Courthouse Boulevard East (US 52 N) | 3.4 mi | |
| Continue onto US 52 N | 0.5 mi | |
| Keep left onto MN 55 W | 8.6 mi | |
| Continue onto MN 55 N | 0.4 mi | |
| Continue onto MN 55 W | 800 feet | |
| Take the ramp towards MN 55 West: Hiawatha Avenue | 1,000 feet | |
| Keep left at the fork | 700 feet | |
| Turn right onto Hiawatha Avenue | 4.6 mi | |
| Keep left onto Hiawatha Avenue (MN 55) | 0.5 mi | |
| Take the ramp towards I 94 West | 0.8 mi | |
| Merge left onto I 94 W | 8.3 mi | |
| Continue onto I 94 N | 1.7 mi | |
| Continue onto I 94 W | 5.9 mi | |
| Continue onto I 94 N | 9.2 mi | |
| Take the ramp towards MN 101 | 0.3 mi | |
| Keep left towards MN 101 | 0.3 mi | |
| Turn left onto MN 101 | 600 feet | |
| Go straight onto CR 81 S | 0.2 mi | |
| Make a slight right to stay on Main Street (CR 150) | 500 feet | |
| You have arrived at your destination |
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La Crosse, Wisconsin - Rogers, Minnesota