John Day-Burns Highway, Pendleton-John Day Highway
335.5 mi7 hours 51 mins
| Head west on South 1st Street | 0 feet | |
| Turn right onto South F Street (US 395) | 22.8 mi | |
| Keep right onto US 395 | 89.6 mi | |
| Turn right onto Central Oregon Highway (US 20) | 25.8 mi | |
| Continue onto Hines Boulevard (US 20) | 0.6 mi | |
| Continue onto West Monroe Street (US 20) | 0.4 mi | |
| Turn left onto North Broadway Avenue (US 20) | 0.6 mi | |
| Go straight onto Seneca Drive (US 20) | 2.2 mi | |
| Turn left onto John Day-Burns Highway (US 395) | 65.4 mi | |
| Continue onto John Day Burns Highway (US 395) | 1.3 mi | |
| Continue onto South Canyon Boulevard (US 395) | 0.6 mi | |
| Turn left onto West Main Street (US 26) | 1.7 mi | |
| Continue onto John Day Highway (US 26) | 6.2 mi | |
| Continue onto East Main Street (US 26) | 0.2 mi | |
| Turn right onto Pendleton-John Day Highway (US 395) | 6.8 mi | |
| Continue straight to stay on Pendleton-John Day Highway (US 395) | 95.7 mi | |
| Continue onto Southwest Birch Place (US 395) | 0.4 mi | |
| Continue slightly left onto Southwest Birch Street (US 395) | 0.3 mi | |
| Make a slight right onto Northwest 2nd Street (US 395) | 200 feet | |
| Continue onto Northeast Alder Street (US 395) | 0.6 mi | |
| Continue onto Pendleton-John Day Highway (US 395) | 11.9 mi | |
| Continue onto Southwest Pendleton-John Day Highway (US 395) | 1.2 mi | |
| Turn left onto Southwest 20th Street | 900 feet | |
| Turn right onto Southwest Court Avenue | 0.3 mi | |
| Go straight onto Southwest Dorion Avenue (US 30) | 0.8 mi | |
| You have arrived at your destination |
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Lakeview, Oregon - Pendleton, Oregon