How to get from Louisville, Kentucky to Darlington, South Carolina

Discover, print or download the driving directions for the best route to go from Louisville, Kentucky to Darlington, South Carolina.

Enlarge the route map Louisville, Kentucky - Darlington, South Carolina

Driving directions from Louisville, Kentucky to Darlington, South Carolina

I 75 $south, I 26 $east

579.6 mi9 hours 2 mins

Head east on West Jefferson Street 400 feet
Turn left onto South 9th Street 600 feet
Take the ramp 500 feet
Keep right at the fork 0.2 mi
Merge right onto I 64 E 177.2 mi
Continue onto I 75 S 64.6 mi
Continue onto I 275 S 0.3 mi
Take the ramp towards I 640 East: Asheville 0.2 mi
Merge left onto I 640 E 6.7 mi
Keep left towards I 40 East: Asheville 28.5 mi
Keep right towards I 40 East: Asheville 76.3 mi
Take the ramp towards I 26 East: Hendersonville 13.3 mi
Continue onto I 26 E 134.0 mi
Take the ramp towards I 20 East: Florence 0.3 mi
Merge left onto I 20 66.2 mi
Take exit 131 towards US 401: Timmonsville 0.3 mi
Turn left onto Lamar Highway (US 401) 5.4 mi
Enter the roundabout and take the 2nd exit onto Lamar Highway (US 401) 200 feet
Exit the roundabout onto Lamar Highway (US 401) 4.9 mi
Continue slightly right onto Pearl Street 1.0 mi
You have arrived at your destination

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Louisville, Kentucky - Darlington, South Carolina

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