I 65 $north, SR 46
93.2 mi1 hour 43 mins
| Head east on West Jefferson Street | 400 feet | |
| Turn left onto South 9th Street | 600 feet | |
| Take the ramp | 500 feet | |
| Keep right at the fork | 0.2 mi | |
| Merge right onto I 64 E | 0.8 mi | |
| Take the ramp on the left towards I 65 South: Nashville | 700 feet | |
| Keep right at the fork | 0.5 mi | |
| Merge left onto Abraham Lincoln Bridge (I 65) | 49.8 mi | |
| Take exit 50A towards US 50 East: North Vernon | 0.3 mi | |
| Turn right onto East Tipton Street (US 50) | 0.3 mi | |
| Turn left onto US 31 | 15.0 mi | |
| Turn right onto SR 46 | 19.6 mi | |
| Continue onto West Main Street (IN 46 E) | 5.2 mi | |
| Turn right onto US 421 | 0.9 mi | |
| Turn left onto West North Street | 400 feet | |
| Turn right onto North Broadway Street | 400 feet | |
| Turn right onto West Washington Street | 100 feet | |
| You have arrived at your destination |
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Louisville, Kentucky - Greensburg, Indiana