How to get from Louisville, KY, USA to Chicago, IL, USA

Discover, print or download the driving directions for the best route to go from Louisville, KY, USA to Chicago, IL, USA.

Enlarge the route map Louisville, KY, USA - Chicago, IL, USA

Driving directions from Louisville, KY, USA to Chicago, IL, USA

I 65 $north, Indiana Toll Road

304.9 mi5 hours 11 mins

Head northeast 200 feet
Continue left onto Auburn Place Drive 800 feet
Turn right onto 3rd Street Road (KY 907) 0.2 mi
Turn left onto New Cut Road (KY 1865) 1.7 mi
Turn right onto Southern Parkway 2.5 mi
Continue onto South 3rd Street (KY 1020) 0.2 mi
Turn right onto Central Avenue 0.7 mi
Turn left onto Crittenden Drive (KY 1631) 0.8 mi
Turn left onto University Blvd 300 feet
Take the ramp on the right 500 feet
Merge left onto I 65 N 115.9 mi
Keep left onto I 65 N 150.3 mi
Turn left onto East 5th Avenue (US 12) 1.0 mi
Continue onto East 4th Avenue (US 12) 0.7 mi
Turn right onto Broadway (SR 53) 500 feet
Take the ramp on the left 0.3 mi
Merge left onto Indiana Toll Road (I 90) 14.2 mi
Continue onto Chicago Skyway (I 90 W) 7.2 mi
Keep left towards I 90 Express 0.4 mi
Merge left onto Dan Ryan Expressway (I 90) 6.4 mi
Take the ramp towards Roosevelt Road 900 feet
Continue onto South Ruble Street 400 feet
Turn left onto West Roosevelt Road 800 feet
Turn right onto South Halsted Street 0.8 mi
Turn left onto West Adams Street 0.7 mi
You have arrived at your destination

Print directions
Louisville, KY, USA - Chicago, IL, USA

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.