I 64 $east, I 75 $south
171.1 mi2 hours 38 mins
| Head east on West Jefferson Street | 400 feet | |
| Turn left onto South 9th Street | 600 feet | |
| Take the ramp | 500 feet | |
| Keep right at the fork | 0.2 mi | |
| Merge right onto I 64 E | 147.3 mi | |
| Take exit 41 towards KY 80: London | 900 feet | |
| Turn left onto Russell Dyche Memorial Highway (KY 80) | 0.6 mi | |
| Continue onto Hal Rogers Parkway | 20.2 mi | |
| Take exit 20 towards KY 80: Manchester | 0.3 mi | |
| Turn left onto KY 80 | 0.2 mi | |
| Continue onto US 421 | 1.8 mi | |
| You have arrived at your destination |
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Louisville, Kentucky - Manchester, Kentucky