I 59 $south, I 10
1,372.5 mi21 hours 39 mins
| Head southeast on Church Street | 0.5 mi | |
| Take the ramp | 0.3 mi | |
| Merge left onto Lynchburg Expressway (US 29 Business W) | 3.7 mi | |
| Take the ramp towards US 501 South | 900 feet | |
| Continue onto Candlers Mountain Road (VA 128) | 0.4 mi | |
| Take the ramp onto US 501 S | 0.3 mi | |
| Keep right at the fork | 0.3 mi | |
| Merge left onto Jerry Falwell Parkway (US 29) | 8.2 mi | |
| Continue onto East Lynchburg Salem Turnpike (US 460) | 15.4 mi | |
| Continue onto Blue Ridge Avenue (US 221) | 0.6 mi | |
| Continue onto West Lynchburg Salem Turnpike (US 221) | 14.6 mi | |
| Continue onto Blue Ridge Boulevard (US 221) | 5.5 mi | |
| Continue onto Challenger Avenue Northeast (US 221) | 0.3 mi | |
| Turn right onto Cloverdale Road (US 220 Alt) | 5.0 mi | |
| Continue onto Roanoke Road (US 220 N) | 0.2 mi | |
| Take the ramp | 800 feet | |
| Merge left onto I 81 S | 225.9 mi | |
| Merge left onto I 40 | 52.7 mi | |
| Keep left towards I 75 South: Chattanooga | 10.2 mi | |
| Keep right onto I 75 S | 800 feet | |
| Keep left onto I 75 S | 72.9 mi | |
| Take the ramp towards I 24 West: Chattanooga | 0.6 mi | |
| Continue towards Chattanooga | 16.7 mi | |
| Take exit 167 on the left towards I 59 South: Birmingham | 0.8 mi | |
| Continue onto I 59 S | 123.2 mi | |
| Take exit 137 on the left towards I-459 South: Tuscaloosa | 0.5 mi | |
| Continue onto John M. Harbert III Freeway (I 459 S) | 22.0 mi | |
| Continue onto I-459 S | 2.0 mi | |
| Continue onto John M. Harbert III Freeway (I 459 S) | 8.6 mi | |
| Keep left towards I 20 West: Tuscaloosa | 1.2 mi | |
| Merge left onto I 20 | 126.9 mi | |
| Continue onto I 20 | 1.8 mi | |
| Keep left towards I 59 South: Laurel | 53.3 mi | |
| Continue onto Lance Corporal Roy M Wheat Memorial Highway (I 59 S) | 106.4 mi | |
| Keep right towards I 12 West: Hammond | 0.5 mi | |
| Continue onto I 12 W | 84.3 mi | |
| Keep left at the fork | 0.9 mi | |
| Merge left onto I 10 | 269.2 mi | |
| Take the ramp on the left towards US 59 South: Downtown | 0.8 mi | |
| Keep left towards I 69 South | 0.4 mi | |
| Merge left onto Eastex Freeway (I 69 S) | 1.2 mi | |
| Continue onto Southwest Freeway (I 69 S) | 32.8 mi | |
| Merge right onto Southwest Freeway (I 69) | 3.3 mi | |
| Take the ramp towards Spur 10: Harledge Road | 0.4 mi | |
| Turn right onto Patton Road (Spur 10) | 1.9 mi | |
| Turn left | 0.3 mi | |
| Turn left onto US 90A | 11.1 mi | |
| Turn left onto South Dill Street (TX 60) | 0.9 mi | |
| Continue onto State Highway 60 (TX 60) | 8.7 mi | |
| Continue onto Mc Kinney Street (TX 60) | 0.4 mi | |
| Turn left onto Walnut Street (FM 1161) | 0.3 mi | |
| Take the ramp on the right | 0.2 mi | |
| Merge left onto US 59 S | 22.5 mi | |
| Take the ramp towards US 59-S Business | 700 feet | |
| Turn left onto US 59-S Business | 400 feet | |
| Make a slight right | 0.3 mi | |
| Turn left | 100 feet | |
| Continue right onto US 59 S | 43.0 mi | |
| Turn right onto Hill Street | 0.2 mi | |
| Turn left onto US 59-T Business | 6.7 mi | |
| Turn left onto North Main Street | 0.5 mi | |
| You have arrived at your destination |
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Lynchburg, Virginia - Victoria, Texas