I 80, Indiana Toll Road
903.3 mi14 hours
| Head west on 2nd Street Northeast | 400 feet | |
| Turn left onto North Washington Avenue (US 65) | 0.3 mi | |
| Make a slight left to stay on North Washington Avenue (US 65) | 800 feet | |
| Go straight onto South Federal Avenue (US 65) | 2.0 mi | |
| Continue onto Partridge Avenue (US 18 Business) | 1.1 mi | |
| Turn left onto US 18 Business | 0.4 mi | |
| Merge left onto Avenue of the Saints (US 18 E) | 73.1 mi | |
| Take the ramp towards US 218 south: Waterloo | 300 feet | |
| Continue towards US 218 south: Waterloo | 0.3 mi | |
| Merge left onto Leo P Rooff Expressway (US 218 S) | 6.7 mi | |
| Continue onto Washington Street (US 218 S) | 2.4 mi | |
| Take the ramp towards I-380 south: Cedar Rapids | 0.2 mi | |
| Keep left towards I-380 south: Cedar Rapids | 6.3 mi | |
| Take the ramp towards I 380 South: Cedar Rapids | 49.2 mi | |
| Continue onto I 380 S | 16.1 mi | |
| Take the ramp towards I 80 East: Iowa City | 0.3 mi | |
| Merge left onto I 80 | 50.2 mi | |
| Take the ramp towards I 280 East: Rock Island | 18.8 mi | |
| Continue onto I 74 E | 8.7 mi | |
| Continue onto I 80 | 144.6 mi | |
| Keep right onto I 80 | 31.4 mi | |
| Continue onto I 94 E | 16.3 mi | |
| Take the ramp towards US 20 East: La Porte | 0.5 mi | |
| Merge left onto US 20 | 3.6 mi | |
| Turn right onto SR 39 | 1.2 mi | |
| Take the ramp on the left | 0.3 mi | |
| Keep left at the fork | 0.4 mi | |
| Merge left onto Indiana Toll Road (I 80) | 107.3 mi | |
| Continue onto Ohio Turnpike (I 80 E) | 141.5 mi | |
| Keep left onto Ohio Turnpike (I 80 E) | 9.2 mi | |
| Keep right onto I 480 E | 9.8 mi | |
| Take the ramp towards I 71: Cleveland | 0.7 mi | |
| Keep left at the fork | 0.3 mi | |
| Merge left onto Berea Freeway | 0.5 mi | |
| Merge right onto I 71 N | 8.5 mi | |
| Merge left onto Innerbelt (I 90) | 3.9 mi | |
| Merge right onto Cleveland Memorial Shoreway (I 90) | 1.5 mi | |
| Continue onto Lakeland Freeway (I 90) | 8.9 mi | |
| Keep right towards I 90 East: Erie Pennsylvania | 164.4 mi | |
| Take exit 57 towards NY 75: Hamburg | 0.8 mi | |
| Keep right at the fork | 0.2 mi | |
| Go straight onto Camp Road (NY 75) | 1.8 mi | |
| Go straight onto Saint Francis Drive (NY 75) | 1.0 mi | |
| Continue onto State Highway 5 (NY 5) | 1.1 mi | |
| Continue onto Lake Shore Road (NY 5) | 0.7 mi | |
| Continue onto Hamburg Turnpike (NY 5) | 1.2 mi | |
| Continue onto Buffalo Skyway (NY 5) | 4.7 mi | |
| Continue onto Delaware Avenue (NY 384) | 800 feet | |
| Enter Niagara Square and take the 5th exit onto Niagara Street | 700 feet | |
| Exit the roundabout onto Niagara Street | 400 feet | |
| Make a sharp left onto South Elmwood Avenue (NY 5) | 0 feet | |
| You have arrived at your destination |
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Mason City, Iowa - Buffalo, New York