I 77 $south, I 70
173.4 mi2 hours 55 mins
| Head northeast on Tremont Avenue Southeast | 100 feet | |
| Turn right onto Erie Street South (SR 241) | 0.4 mi | |
| Turn right onto Walnut Road Southwest | 800 feet | |
| Turn left onto Great Lakes Boulevard Northwest (SR 21 S) | 2.3 mi | |
| Continue onto Erie Avenue Southwest (US 62) | 2.2 mi | |
| Continue onto North Main Street (US 62) | 0.8 mi | |
| Continue onto Erie Avenue Southwest (SR 21) | 6.7 mi | |
| Continue onto US 250 | 2.9 mi | |
| Take the ramp on the right onto US 250 E | 6.6 mi | |
| Keep left onto I 77 S | 37.0 mi | |
| Take exit 44A on the left towards I 70 East: Wheeling | 0.5 mi | |
| Merge right onto I 70 | 39.2 mi | |
| Keep right onto I 470 E | 10.8 mi | |
| Merge left onto I 70 | 30.1 mi | |
| Take the ramp towards I-79 south: Morgantown | 19.6 mi | |
| Take the ramp towards PA 21: Masontown | 900 feet | |
| Keep left at the fork | 400 feet | |
| Merge right onto Roy E. Furman Highway (PA 21 E) | 8.8 mi | |
| Turn left onto West George Street | 1.5 mi | |
| Turn right onto North Eighty Eight Road (PA 88) | 400 feet | |
| Continue onto South Vine Street (PA 88) | 0.3 mi | |
| Continue onto Eighty Eight Road (PA 88) | 0.3 mi | |
| Make a slight left onto Nemacolin Road | 2.2 mi | |
| Make a slight right onto Pershing Boulevard | 0.6 mi | |
| You have arrived at your destination |
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Massillon, Ohio - Nemacolin, Pennsylvania