I 40, Vietnam Veteran's Memorial Highway
1,001.7 mi14 hours 34 mins
| Head west on Poplar Avenue | 900 feet | |
| Turn right onto North Front Street | 0.3 mi | |
| Take the ramp on the left | 0.4 mi | |
| Merge left onto Hernando de Soto Bridge (I 40) | 7.8 mi | |
| Keep left onto I 40 | 442.7 mi | |
| Keep left onto Tinker Diagonal (I 40 W) | 12.3 mi | |
| Continue onto Crosstown Expressway (I 35 S) | 0.9 mi | |
| Keep right towards I 235 North: Oklahoma Health Center | 4.7 mi | |
| Continue towards I 40 West: Amarillo | 64.8 mi | |
| Continue onto Senator Ed Berrong Memorial Highway (I 40 W) | 2.6 mi | |
| Continue onto Korean War Veterans Memorial Highway (I 40 W) | 24.1 mi | |
| Continue onto Great Western Cattle Trail (I 40 W) | 10.6 mi | |
| Continue onto Korean War Veterans Memorial Highway (I 40 W) | 4.2 mi | |
| Turn right onto North Eastern Avenue | 200 feet | |
| Turn left onto East 3rd Street | 1.1 mi | |
| Make a slight left onto US Historic 66 | 6.6 mi | |
| Take the ramp towards I 40 West: Amarillo | 0.4 mi | |
| Merge left onto Korean War Veterans Memorial Highway (I 40 W) | 257.8 mi | |
| Continue onto I 40 | 106.1 mi | |
| Take the ramp towards US 285: Vaughn | 0.3 mi | |
| Turn right onto US 285 | 41.3 mi | |
| Turn left onto US 285 | 7.5 mi | |
| Take the ramp towards US 84: Santa Fe Plaza | 0.5 mi | |
| Continue onto South Saint Francis Drive (US 84) | 3.4 mi | |
| Continue onto North Saint Francis Drive (US 84) | 700 feet | |
| Turn right onto Paseo de Peralta (NM 475) | 0.9 mi | |
| You have arrived at your destination |
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Memphis, Tennessee - Santa Fe, New Mexico