I 44 $east, I 70
818.6 mi13 hours 14 mins
| Head southeast on Mena Street (AR 88) | 0.3 mi | |
| Turn left onto Pickering (US 59) | 0.8 mi | |
| Continue onto US 59 | 4.9 mi | |
| Continue onto US 71 N | 25.6 mi | |
| Turn right onto South Main Street (US 71B) | 6.0 mi | |
| Go straight onto US 71 N | 37.9 mi | |
| Take the ramp onto US 71 N | 12.0 mi | |
| Keep right towards Little Rock | 4.6 mi | |
| Take the ramp towards I 49 North: Fayetteville | 0.7 mi | |
| Continue onto I 49 N | 24.6 mi | |
| Take the ramp towards Winslow | 0.9 mi | |
| Merge left onto I 49 N | 7.1 mi | |
| Take the ramp towards West Fork | 0.7 mi | |
| Merge left onto I 49 N | 13.1 mi | |
| Keep left onto I 49 N | 19.4 mi | |
| Continue onto I 49 N | 56.1 mi | |
| Take the ramp towards I 44 East: Springfield | 52.0 mi | |
| Continue onto I 44 E | 227.3 mi | |
| Keep right towards I 55 North | 0.8 mi | |
| Keep right towards IL 3 South: East Saint Louis | 1.2 mi | |
| Merge left onto I 55 N | 0.9 mi | |
| Continue onto I 55 N | 700 feet | |
| Keep left towards I 55 North: Chicago | 0.6 mi | |
| Merge right onto I 55 N | 15.5 mi | |
| Keep right towards I 70 East: Indianapolis | 223.7 mi | |
| Keep right towards 10 Street | 2.2 mi | |
| Take the ramp towards Rural Street | 900 feet | |
| Make a slight right onto North Rural Street | 200 feet | |
| Continue onto North Keystone Avenue | 2.7 mi | |
| Turn right onto East Fall Creek Parkway North Drive | 1,000 feet | |
| Continue onto Binford Boulevard | 5.8 mi | |
| Continue onto I 69 N | 3.4 mi | |
| Keep left onto I 69 N | 21.3 mi | |
| Continue onto I 69 N | 38.6 mi | |
| Take exit 264 towards SR 18: Marion | 0.3 mi | |
| Turn right onto East North 00 South (SR 18) | 2.4 mi | |
| Turn left onto North 900 East (SR 5) | 4.4 mi | |
| You have arrived at your destination |
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Mena, Arkansas - Van Buren, Indiana