I 57 $north, I 75 $north
1,018.5 mi15 hours 46 mins
| Head northwest on Old Highway 78 (MS 178) | 0.4 mi | |
| Continue onto Old US Highway 78 | 0.8 mi | |
| Turn right onto Lamar Avenue (US 78) | 6.7 mi | |
| Take the ramp towards I 240: Nashville | 600 feet | |
| Keep left towards I 240 West: Saint Louis | 0.7 mi | |
| Merge left onto I 240 W | 4.1 mi | |
| Continue onto I 55 N | 5.5 mi | |
| Take the ramp towards I 55 North: Saint Louis | 7.9 mi | |
| Keep right onto I 55 N | 131.2 mi | |
| Take the ramp towards I 57 North: Chicago | 0.5 mi | |
| Merge left onto Interstate 57 (I 57 N) | 115.8 mi | |
| Continue onto I 57 N | 69.4 mi | |
| Keep left towards I 57 North: Chicago | 155.0 mi | |
| Keep left onto I 57 N | 26.4 mi | |
| Take exit 345A towards I 80 East: Indiana | 0.5 mi | |
| Merge left onto I 80 | 3.0 mi | |
| Keep right onto I 80 | 31.4 mi | |
| Continue onto I 94 E | 130.1 mi | |
| Take the ramp towards I 69: Fort Wayne | 900 feet | |
| Keep left at the fork | 0.3 mi | |
| Keep right towards I 69 North: Lansing | 0.4 mi | |
| Keep left towards I 69 North | 0.5 mi | |
| Merge left onto I 69 N | 33.7 mi | |
| Keep left towards I 69 North: Lansing | 1.4 mi | |
| Continue onto I-69 | 0.5 mi | |
| Take exit 95 towards I 496: Downtown Lansing | 0.7 mi | |
| Continue onto Ransom E Olds Freeway (I 496 E) | 7.4 mi | |
| Take the ramp towards US 127 North: East Lansing | 0.5 mi | |
| Keep right at the fork | 0.3 mi | |
| Merge left onto US 127 N | 110.0 mi | |
| Continue onto US 127:FUT I-73 N | 27.5 mi | |
| Merge right onto I 75 N | 144.5 mi | |
| Take exit 394 towards Easterday Avenue | 0.3 mi | |
| Turn right onto West Easterday Avenue | 0.8 mi | |
| Turn left onto Ashmun Street (BS I-75) | 300 feet | |
| You have arrived at your destination |
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Mineral Wells, Olive Branch, Mississippi - Sault Ste Marie, Michigan