PA 28; PA 66, PA 28
116.4 mi2 hours 24 mins
| Head east on 11th Street | 500 feet | |
| Turn right onto Barnes Street | 0.2 mi | |
| Turn left onto 9th Street | 200 feet | |
| Turn right onto Constitution Boulevard | 0.2 mi | |
| Turn left onto 7th Street (PA 56) | 0.4 mi | |
| Turn left onto Stevenson Boulevard (PA 56) | 0.7 mi | |
| Make a slight right onto PA 366 W | 2.2 mi | |
| Continue onto Ross Street (PA 366 W) | 900 feet | |
| Continue onto Bull Creek Road (PA 366 W) | 0.6 mi | |
| Take the ramp on the right | 0.3 mi | |
| Merge left onto Allegheny Valley Expressway (PA 28 N) | 17.9 mi | |
| Keep right towards US 422 East: Kittanning | 0.6 mi | |
| Merge left onto US 422 E | 4.8 mi | |
| Continue onto PA 28 | 37.1 mi | |
| Take the ramp on the right onto PA 28 Truck N | 17.8 mi | |
| Take the ramp towards US 219: DuBois | 0.2 mi | |
| Make a slight left | 200 feet | |
| Merge left onto Rich Highway (US 219) | 7.5 mi | |
| Continue onto Clark Street (US 219) | 600 feet | |
| Turn right onto Main Street (US 219) | 13.5 mi | |
| Turn right onto Shelvey Summit Road (PA 948) | 3.3 mi | |
| Continue onto West Main Street (PA 948) | 2.3 mi | |
| Continue onto Fairview Road (PA 948) | 1.9 mi | |
| Turn left onto Million Dollar Highway (PA 255) | 4.2 mi | |
| Continue onto South Saint Marys Street (PA 255 N) | 800 feet | |
| Turn right onto Railroad Street (PA 120 E) | 200 feet | |
| Turn left onto South Michael Street (PA 120 W) | 200 feet | |
| Make a slight left onto PA 120 W | 200 feet | |
| You have arrived at your destination |
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New Kensington, Pennsylvania - St Marys, Pennsylvania