I 20, I 20; I 59 $south
1,246.9 mi20 hours 32 mins
| Head south on 2nd Ave South | 0.2 mi | |
| Turn right onto US 17 | 5.5 mi | |
| Take the ramp towards SC 22 West: Conway | 0.3 mi | |
| Continue onto William H. Alford Bridge | 0.3 mi | |
| Merge left onto William H. Alford Bridge (SC 22 W) | 0.5 mi | |
| Continue onto Veterans Highway (SC 22 W) | 27.4 mi | |
| Keep right at the fork | 0.2 mi | |
| Merge left onto US 501 | 21.1 mi | |
| Go straight onto SC 576 N | 3.2 mi | |
| Continue onto US 76 | 22.5 mi | |
| Turn right onto I 20 Business | 421.7 mi | |
| Take the ramp towards I 459: Montgomery | 0.3 mi | |
| Keep left towards I 459 South: Montgomery | 0.8 mi | |
| Merge left onto John M. Harbert III Freeway (I 459 S) | 17.8 mi | |
| Continue onto I-459 S | 2.0 mi | |
| Continue onto John M. Harbert III Freeway (I 459 S) | 8.6 mi | |
| Keep left towards I 20 West: Tuscaloosa | 1.2 mi | |
| Merge left onto I 20 | 126.9 mi | |
| Continue onto I 20 | 1.8 mi | |
| Keep right towards I 20 West: Jackson | 85.1 mi | |
| Merge left onto I 20 | 1.6 mi | |
| Keep right towards I 20 West: Vicksburg | 39.1 mi | |
| Merge right onto I 20 | 3.8 mi | |
| Keep right onto I 20 | 255.1 mi | |
| Take the ramp towards US 271: Gladewater | 0.2 mi | |
| Merge left onto US 271 | 9.4 mi | |
| Turn right onto East Northeast Loop 323 (Loop 323) | 1.6 mi | |
| Continue onto West Northwest Loop 323 (Loop 323) | 4.3 mi | |
| Continue onto South Southwest Loop 323 (Loop 323) | 0.6 mi | |
| Turn right onto Chandler Highway (TX 31) | 1.6 mi | |
| Continue onto State Highway 31 West (TX 31) | 28.6 mi | |
| Take the ramp | 0.9 mi | |
| Continue onto US 175 | 5.6 mi | |
| Take the ramp onto TX 31 | 800 feet | |
| Keep left at the fork | 400 feet | |
| Turn right onto TX 31-H Business | 80.3 mi | |
| Continue onto US 84 | 5.4 mi | |
| Turn left onto Interstate Highway 35 Service Road | 1,000 feet | |
| Take the ramp on the left | 0.2 mi | |
| Merge left onto Jack Kultgen Freeway (I 35 S) | 5.1 mi | |
| Keep left onto Jack Kultgen Expressway (I 35 S) | 13.3 mi | |
| Keep left onto I 35 S | 25.6 mi | |
| Keep right towards US 190 West: Killeen | 10.5 mi | |
| Take the ramp towards US 190 Business West | 6.1 mi | |
| You have arrived at your destination |
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North Myrtle Beach, South Carolina - Killeen, Texas