I 26 $east, I 95 $south
496.6 mi7 hours 38 mins
| Head southwest on Russell Street (SC 33) | 300 feet | |
| Turn left onto Broughton Street (US 178 Business) | 0.2 mi | |
| Turn left onto John C Calhoun Drive (US 301) | 1.8 mi | |
| Turn right onto Five Chop Road (US 301) | 6.4 mi | |
| Take the ramp | 0.4 mi | |
| Merge left onto I 26 E | 13.6 mi | |
| Take the ramp towards I 95 South: Savannah | 0.9 mi | |
| Merge left onto I 95 S | 229.7 mi | |
| Take the ramp towards I 90 | 0.5 mi | |
| Keep right at the fork | 0.2 mi | |
| Keep left at the fork | 0.2 mi | |
| Merge left onto I 95 S | 220.1 mi | |
| Take the ramp towards FL 70: Okeechobee | 0.4 mi | |
| Keep right towards FL 70: Okeechobee | 700 feet | |
| Merge left onto Okeechobee Road (FL 70) | 0.5 mi | |
| Take the ramp on the left | 0.2 mi | |
| Keep left at the fork | 0.5 mi | |
| Merge left onto Florida's Turnpike | 9.4 mi | |
| Take the ramp towards Port Saint Lucie | 1.0 mi | |
| Continue onto Southwest Bayshore Boulevard | 500 feet | |
| Turn right onto Southeast Port Saint Lucie Boulevard | 4.1 mi | |
| Turn right onto US 1 | 2.0 mi | |
| Turn left onto Northwest Jensen Beach Boulevard (FL 732) | 1.2 mi | |
| Continue onto Northeast Jensen Beach Boulevard (FL 732) | 1.5 mi | |
| Enter the roundabout and take the 3rd exit onto Northeast Pineapple Avenue | 200 feet | |
| Exit the roundabout onto Northeast Pineapple Avenue | 0.5 mi | |
| Enter the roundabout and take the 3rd exit onto Northeast Indian River Drive (CR 707) | 200 feet | |
| Exit the roundabout onto Northeast Indian River Drive (CR 707) | 0.7 mi | |
| Turn left onto Northeast Skyline Drive | 300 feet | |
| You have arrived at your destination |
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Orangeburg, South Carolina - Jensen Beach, Florida