How to get from Orlando, FL to Sanibel, FL

Discover, print or download the driving directions for the best route to go from Orlando, FL to Sanibel, FL.

Enlarge the route map Orlando, FL - Sanibel, FL

Driving directions from Orlando, FL to Sanibel, FL

I 4 $west, US 17

175.6 mi3 hours 24 mins

Head north on Magnolia Avenue 100 feet
Turn left onto South Street 0.3 mi
Take the ramp on the left 0.2 mi
Merge left onto I 4 W 34.6 mi
Take the ramp towards CR 557: Lake Alfred 900 feet
Turn right onto Old Grade Road (CR 557) 6.4 mi
Continue onto Pomelo Street (CR 557) 400 feet
Turn right onto Shinn Boulevard (US 17) 0.6 mi
Continue onto Lake Shore Way (US 17) 0.6 mi
Go straight onto US 17 45.7 mi
Continue onto US 17 18.3 mi
Turn left onto Magnolia Street (FL 70) 0.7 mi
Continue onto Oak Street (FL 70) 1.0 mi
Turn right onto Hog Bay Avenue (FL 31) 5.6 mi
Turn right onto FL 31 30.8 mi
Turn right onto Palm Beach Boulevard (FL 80) 2.5 mi
Take the ramp on the left 0.5 mi
Merge left onto I 75 S 4.3 mi
Take the ramp towards SR 884: Fort Myers 0.3 mi
Keep right towards SR 884: Colonial Blvd 300 feet
Merge left onto Colonial Boulevard (FL 884) 5.4 mi
Take the ramp towards FL 867 0.3 mi
Go straight 200 feet
Make a slight left onto McGregor Boulevard (FL 867) 6.6 mi
Turn right to stay on McGregor Boulevard (CR 867) 4.8 mi
Continue onto Sanibel Causeway Boulevard (Span A) 2.8 mi
Continue onto Causeway Road 0.4 mi
Turn right onto Periwinkle Way 2.2 mi
Turn right onto Dunlop Road 700 feet
You have arrived at your destination

Print directions
Orlando, FL - Sanibel, FL

At How to get from we offer the best route to any destination. We use the most advanced technologies of maps representation, route calculation, traffic information updated in real time and distance calculator to give you a detailed itinerary to get to your destination.